Evidence map›Paper›PMID 21330743›Full record

ArticleJournal of infection in developing countries2011

Distribution of HIV-1 and HSV-2 epidemics in Chad revealing HSV-2 hot-spot in regions of high-risk HIV spread.

Charlotte Charpentier, Donato Koyalta, Montana Ndinaromtan, Bagamla Tchobkréo, Mohammad-Ali Jenabian, Nesrine Day, Ali Si-Mohamed, Helen Weiss, Laurent Bélec

Open access · goldAbstract read
In one paragraph

Article in Journal of infection in developing countries, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. School Support as Structural HIV Prevention for Adolescent Orphans in Western Kenya.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2018
    Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 4 countries.

Charlotte CharpentierLaboratoire de Virologie, Hôpital Européen Georges Pompidou, and Faculté de Médecine Paris Descartes, Paris, France. charlotte.charpentier@bch.aphp.fr
Donato Koyalta
Montana Ndinaromtan
Bagamla Tchobkréo
Mohammad-Ali Jenabian
Nesrine Day
Ali Si-Mohamed
Helen Weiss
Laurent Bélec
Hôpital Européen Georges-Pompidou · FRUniversité Paris Cité · FRUniversity of N'Djamena · TDInstitut National de la Statistique · MGUniversity of London · GB

Funding

Medical Research Council G0700837
6 · The paper itself

Abstract

introductionHerpes Simplex Virus-2 (HSV-2) is known to be a potent co-factor of Human Immunodeficiency type 1 virus (HIV-1) heterosexual transmission. We were interested in assessing the distribution of HIV-1 and HSV-2 epidemics at the national level in Chad. METHODOLOGY: In 2007, a population-based anonymous serosurvey for HIV-1 and HSV-2 infections, using dried blood spots, was conducted. The study included 548 adults living in 15 regions of Chad. After specimen elution, serological testing for HIV and HSV-2 infections was performed.

resultsCountrywide, the HIV-1 and HSV-2 seroprevalences were 11.1% and 15.7%, respectively. A positive correlation was observed with the highest HIV-1 prevalence seen in regions of the highest HSV-2 prevalence, especially in two conflict-affected eastern provinces of Darfur.

conclusionUrgent public health interventions are needed in regions of Chad where high HSV-2 prevalence may be increasing the risk of HIV propagation.

Indexed as

AdultAnimalsChadComorbidityFemaleHerpes GenitalisHerpesvirus 2, HumanHIV-1HIV InfectionsHumansMaleSeroepidemiologic Studies

Identifiers

PMID21330743
PMCPMC3763473
OpenAlexW2125260963

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.