ArticleJournal of clinical epidemiology2011
Preconsent education about research processes improved African Americans' willingness to participate in clinical research.
Article in Journal of clinical epidemiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Audio-visual presentation of information for informed consent for participation in clinical trials.The Cochrane database of systematic reviews · 2014Pooled it
- A systematic review of barriers and facilitators to minority research participation among African Americans, Latinos, Asian Americans, and Pacific Islanders.American journal of public health · 2014Pooled it
- Pooled it
- Beyond the Guinea Pig Myth: Understanding Complex Attitudes Toward Clinical Trials Participation in a Community Clinic.Journal of cancer education : the official journal of the American Association for Cancer Education · 2026Article
- Guide on Selection of Optimal Motivational Themes for Use in a Clinical Trial Recruiting Black US Adults: Survey Study.Journal of medical Internet research · 2026Article
- Racial Disparities in Parkinson Disease Clinical Phenotype, Management, and Genetics: Protocol for a Prospective Observational Study.JMIR research protocols · 2025Observational
- The role of individual differences and attitude in willingness to participate in TMS studies.Behavior research methods · 2025Article
- Winning hearts & minds: prostate cancer outreach and clinical trial enrollment in minority men.Translational cancer research · 2024Review
- Insights From African American Older Adults on Brain Health Research Engagement: "Need to See the Need".Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2021Article
- Participatory Genomic Testing Can Effectively Disseminate Cardiovascular Pharmacogenomics Concepts within Federally Qualified Health Centers: A Feasibility Study.Ethnicity & disease · 2020Article
- Mock Recruitment for the Study of Antimalarials in an Incomplete Lupus Erythematosus Trial.Arthritis care & research · 2019Article
- Lung Cancer Screening and Epigenetics in African Americans: The Role of the Socioecological Framework.Frontiers in oncology · 2019Article
- Accessing Disadvantaged Pregnant Women in Houston, Texas, and Characterizing Biomarkers of Metal Exposure: A Feasibility Study.International journal of environmental research and public health · 2017Article
- Challenges and Considerations Related to Studying Dementia in Blacks/African Americans.Journal of Alzheimer's disease : JAD · 2017Article
- Willingness to participate in health research: Tunisian survey.BMC medical ethics · 2016Article
- Article
- Is religiosity related to attitudes toward clinical trials participation?Journal of cancer education : the official journal of the American Association for Cancer Education · 2015Article
- Recruiting for epigenetic research: facilitating the informed consent process.Nursing research and practice · 2013Article
- Improving informed consent with minority participants: results from researcher and community surveys.Journal of empirical research on human research ethics : JERHRE · 2012Article
- Predictors of Participation in Clinical Research.Nursing researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
objectiveTo determine whether preconsent education about research processes and protections affects the willingness of African Americans to participate. STUDY DESIGN AND
settingThis study examined the willingness of 192 African American outpatients (stratified by age, gender, and education) to participate in a hypothetical clinical study under varying consent conditions: phase I participants underwent a typical informed consent process and were asked to indicate whether they would be willing to participate in the hypothetical clinical study and the reasons for their decision; their responses were used to develop a preconsent educational digital video disk (DVD). Phase II participants viewed the DVD before the consent process. We compared the proportion of those who stated they were willing to participate in the clinical study using Fisher's exact tests and used qualitative methods to analyze open-ended responses.
resultsWhen the consent process included education about research processes and protections, significantly more patients reported willingness to participate in the hypothetical clinical study (43% vs. 27%; P=0.002). Patients receiving preconsent education were significantly less likely to cite mistrust, fear of side effects, lack of perceived benefits, and privacy as reasons for not participating.
conclusionPreconsent education may improve the willingness of African Americans to participate in clinical research and may address important concerns about research participation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.