Evidence map›Paper›PMID 21329402›Full record

ArticleDrugs & aging2011

Potentially inappropriate medication use among Finnish non-institutionalized people aged ≥65 years: a register-based, cross-sectional, national study.

Saija Leikola, Maarit Dimitrow, Alan Lyles, Kaisu Pitkälä, Marja Airaksinen

Registry-linked trialAbstract read
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In one paragraph

Article in Drugs & aging, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02545257 (Development of a Coordinated, Community-Based Medication Management Model for Home-Dwelling Aged in Primary Care), which is not on this map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02545257 nacompletednot on this mapstarted 2015, after this paper: background citation

Development of a Coordinated, Community-Based Medication Management Model for Home-Dwelling Aged in Primary Care

TypeinterventionalSponsorUniversity of HelsinkiRan2015 to 2018Enrolled191ConditionsDrug Therapy, Combination, Inappropriate Prescribing, PolypharmacyArmsCoordinated medication management model
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
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  9. Medication Risk Management in Routine Dispensing in Community Pharmacies.International journal of environmental research and public health · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Saija LeikolaDivision of Social Pharmacy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. saija.leikola@iki.fi
Maarit Dimitrow
Alan Lyles
Kaisu Pitkälä
Marja Airaksinen
University of Helsinki · FIHelsinki University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Beers criteria and their modifications are the most frequently used tools for measuring potentially inappropriate medication (PIM) use among older people. The prevalence of such use in various settings has been high, but no data have been reported for an entire national non-institutionalized elderly population, nor is there information on the reimbursement costs for those medications.

objectiveTo determine the prevalence of PIM use according to the Beers 2003 criteria, independent of diagnoses, among Finnish non-institutionalized people aged ≥65 years, and the reimbursement costs for these medications.

methodsA register-based cross-sectional national study used drug reimbursement data from Finland's Social Insurance Institution (SII). These data cover the entire non-institutionalized population aged ≥65 years in 2007. The number of persons who received reimbursements for each PIM according to the Beers 2003 criteria and the total annual reimbursement costs for PIMs were calculated. Indirect costs were excluded.

resultsOf the non-institutionalized population aged ≥65 years in Finland (n = 841,509), 14.7% (n = 123,545) had received PIMs according to the Beers 2003 criteria. Temazepam >15 mg/day was clearly the most commonly reimbursed PIM (4.4% of the population aged ≥65 years), followed by amitriptyline (2.0%) and diazepam (1.8%). The SII paid drug reimbursements of €2.9 million for PIMs, which was 0.7% of the total drug reimbursements (€421 million) for people aged ≥65 years in Finland in 2007.

conclusionsThe use of PIMs among outpatients aged ≥65 years in Finland (14.7%) was less than in several earlier large-scale studies in other countries (17-42%) and reimbursement costs were modest, mainly as a result of the limited availability in Finland of medicines identified as PIMs by the Beers 2003 criteria. However, benzodiazepines were commonly used and actions to improve medication safety should target reducing their use.

Indexed as

RegistriesAgedCross-Sectional StudiesDrug CostsFinlandHumansInsurance, Health, ReimbursementMedication Errors

Identifiers

PMID21329402
OpenAlexW2249212509

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.