Evidence map›Paper›PMID 21328082›Full record

ReviewCurrent heart failure reports2011

Vitamin D in chronic heart failure.

Miles D Witham

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current heart failure reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Observational
  4. Review
  5. Vitamin D-Parathyroid Hormone-Fibroblast Growth Factor 23 Axis and Cardiac Remodeling.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Observational
  11. Article
  12. Sarcopenia in heart failure: mechanisms and therapeutic strategies.Journal of geriatric cardiology : JGC · 2016
    Review
  13. Review
  14. Micronutrients in chronic heart failure.Current heart failure reports · 2013
    Review
  15. The role of iron, omega-3 Fatty acids, and vitamins in heart failure.Current treatment options in cardiovascular medicine · 2012
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Miles D WithamSection of Ageing and Health, Centre for Cardiovascular and Lung Biology, Division of Medical Sciences, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, Scotland, UK, m.witham@dundee.ac.uk.
University of Dundee · GB

Funding

Chief Scientist Office
6 · The paper itself

Abstract

Recent evidence suggests a number of mechanisms whereby vitamin D may positively influence the pathophysiology of heart failure. These include actions on the renin-angiotensin system, calcium handling, reduction of proinflammatory cytokines, and improvements in endothelial function and blood pressure. Observational data suggest that low vitamin D levels are common in patients with heart failure and are associated with worse exercise capacity and natriuretic peptide levels. Little interventional data are currently available, but evidence to date does not support vitamin D supplementation, even in patients with low vitamin D levels. Further studies are needed to establish whether larger doses of vitamin D given over a longer period of time can reduce symptoms, hospitalization, and mortality in heart failure.

Indexed as

Chronic DiseaseHeart FailureHumansVitamin DVitamin D

Identifiers

PMID21328082
OpenAlexW2074435879

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.