Trial reportEuropean journal of applied physiology2011
Physiological elevation of endogenous hormones results in superior strength training adaptation.
Trial report in European journal of applied physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 1 synthesis or guideline pooled it, 111 citations in OpenAlex.
- Effect of Training Leading to Repetition Failure on Muscular Strength: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2016Pooled it
- Vitamin D supplementation does not enhance resistance training-induced gains in muscle strength and lean body mass in vitamin D deficient young men.European journal of applied physiology · 2021Trial
- Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men.Journal of cachexia, sarcopenia and muscle · 2019Trial
- Lower body blood flow restriction training may induce remote muscle strength adaptations in an active unrestricted arm.European journal of applied physiology · 2018Trial
- Critical difference applied to exercise-induced salivary testosterone and cortisol using enzyme-linked immunosorbent assay (ELISA): distinguishing biological from statistical change.Journal of physiology and biochemistry · 2014Trial
- Hormonal and neuromuscular responses to mechanical vibration applied to upper extremity muscles.PloS one · 2014Trial
- Resistance exercise-induced circulating factors influence the damaged skeletal muscle proteome in a sex-dependent manner.Physiological reports · 2025Article
- The role of resistance exercise-induced local metabolic stress in mediating systemic health and functional adaptations: could condensed training volume unlock greater benefits beyond time efficiency?Frontiers in physiology · 2025Review
- Free-Weight Resistance Training Enhances Core Muscle Strength but Does Not Translate to Improved Athletic Performance in Adolescent Canoe/Kayak Athletes.Children (Basel, Switzerland) · 2024Article
- Vertical Strength Transfer Phenomenon Between Upper Body and Lower Body Exercise: Systematic Scoping Review.Sports medicine (Auckland, N.Z.) · 2024Article
- Artificial intelligence in sport: Exploring the potential of using ChatGPT in resistance training prescription.Biology of sport · 2024Article
- Salivary testosterone and cortisol responses to seven weeks of practical blood flow restriction training in collegiate American football players.Frontiers in physiology · 2024Article
- Sex differences and athletic performance. Where do trans individuals fit into sports and athletics based on current research?Frontiers in sports and active living · 2023Review
- Acute changes in serum and skeletal muscle steroids in resistance-trained men.Frontiers in endocrinology · 2023Article
- Chronic obstructive pulmonary disease does not impair responses to resistance training.Journal of translational medicine · 2021Article
- Integrating Transwomen and Female Athletes with Differences of Sex Development (DSD) into Elite Competition: The FIMS 2021 Consensus Statement.Sports medicine (Auckland, N.Z.) · 2021Review
- Performance Comparisons of Youth Weightlifters as a Function of Age Group and Sex.Journal of functional morphology and kinesiology · 2021Article
- Effects of Different Types of Lower Body Resistance Exercise on Upper-body Strength in Men and Women, with Special Reference to Anabolic Hormones.International journal of exercise science · 2021Article
- Differential Autophagy Response in Men and Women After Muscle Damage.Frontiers in physiology · 2021Article
- Resistance Training and Skeletal Muscle Protein Metabolism in Eumenorrheic Females: Implications for Researchers and Practitioners.Sports medicine (Auckland, N.Z.) · 2019Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to determine the influence of transiently elevated endogenous hormone concentrations during exercise on strength training adaptations. Nine subjects performed four unilateral strength training session per week on the elbow flexors for 11 weeks. During two of the weekly sessions, leg exercises were performed to acutely increase the systemic anabolic hormone concentration immediately before the exercises for one of the elbow flexors (L + A). On the two other weekly training sessions, the contralateral elbow flexors were trained without prior leg exercises (A). By randomizing one arm of the subjects to serve as a control and the other as experimental, both conditions have the same nutritional and genetic environment. Serum testosterone and growth hormone was significantly increased during the L - A training session, while no hormonal changes occurred in the A session. Both A and L + A increased 1RM in biceps curl, peak power in elbow flexors at 30 and 60% of 1RM, and muscle volume of the elbow flexors (p < 0.05). However, only L + A achieved increase in CSA at the part of the arm flexors with largest cross sectional area (p < 0.001), while no changes occurred in A. L + A had superior relative improvement in 1RM biceps curl and favorable muscle adaptations in elbow flexors compared to A (p < 0.05). In conclusion, performing leg exercises prior to arm exercises, and thereby increasing the levels of serum testosterone and growth hormone, induced superior strength training adaptations compared to arm training without acute elevation of hormones.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.