Evidence map›Paper›PMID 21327529›Full record

Trial reportJournal of general internal medicine2011

Improving the follow-up of positive hemoccult screening tests: an electronic intervention.

Linda L Humphrey, Jackilen Shannon, Melissa R Partin, Jean O'Malley, Zunqiu Chen, Mark Helfand

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of general internal medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00122187 (Translation of Colorectal Cancer Screening Guidelines), which is not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00122187 nacompletednot on this map

Translation of Colorectal Cancer Screening Guidelines: A System Intervention

TypeinterventionalSponsorUS Department of Veterans AffairsRan2005 to 2008Enrolled8ConditionsColorectal CancerArmsElectronic Consult System
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Trial
  7. Trial
  8. Screening for Colorectal Cancer.Hematology/oncology clinics of North America · 2022
    Review
  9. What Multilevel Interventions Do We Need to Increase the Colorectal Cancer Screening Rate to 80%?Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Time to Colonoscopy after Positive Fecal Blood Test in Four U.S. Health Care Systems.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2016
    Article
  19. Article
  20. Organizational predictors of colonoscopy follow-up for positive fecal occult blood test results: an observational study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2015
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Linda L HumphreyThe Portland Veterans Affairs Medical Center, Portland, OR 97239, USA. Linda.Humphrey@va.gov
Jackilen Shannon
Melissa R Partin
Jean O'Malley
Zunqiu Chen
Mark Helfand

Funding

OREGON CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024140 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$61.1M
NCRR NIH HHS UL1 RR024140NCRR NIH HHS UL1 RR024140 01
6 · The paper itself

Abstract

backgroundFour population-based studies of screening for CRC with fecal occult blood testing (FOBT) have shown that mortality can be significantly reduced. However, nearly half of all positive screening tests are not appropriately evaluated.

objectivesWe evaluated whether an electronic record intervention improved the follow-up of patients with a positive FOBT (FOBT+) result.

designWe conducted a cluster randomized trial involving four Veteran's Affairs (VA) medical centers pair-matched by colonoscopy volume and randomized within the pair to receive the electronic intervention or usual care.

participantsAll patients with FOBT+ results at participating facilities during a matched pre- and post-intervention time period.

interventionsIn the two intervention sites, an electronic consult that imported relevant clinical information was automatically submitted to the gastroenterology (GI) clinic for all FOBT+ patients at the time the result was recorded in the laboratory. In both intervention and control sites (usual care), PCPs continued to be notified of FOBT+ results in the usual manner MEASURES: Pre- and post-intervention changes in the proportion of FOBT+ patients having: (1) a GI consult or (2) a GI consult plus complete diagnostic evaluation (CDE) of the colon within 30, 90 and 180 days were compared across intervention and control sites. Log rank tests were used to determine statistical significance.

resultsThe 30-, 90- and 180-day GI consult rates improved 21-33 % (p < 0.001) among intervention sites, but did not change in the usual care sites. Thirty-, 90- and 180-day CDE rates improved 9-31% (p < 0.03) in intervention sites, but did not significantly change in the usual care sites. Time to GI consult and CDE decreased significantly over time in the intervention sites (p < 0.001), but remained unchanged in the usual care sites.

conclusionsThe relatively simple electronic intervention evaluated can significantly improve the follow-up of FOBT+ results. Interventions such as this could improve patient care and may be applicable to other practice settings, as well as other types of tests.

Indexed as

Occult BloodAgedAged, 80 and overColorectal NeoplasmsEarly Detection of CancerElectronic Health RecordsFemaleFollow-Up StudiesHumansMaleMass ScreeningMiddle AgedPredictive Value of TestsReferral and ConsultationUnited StatesUnited States Department of Veterans Affairs

Identifiers

PMID21327529
PMCPMC3138585

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.