Evidence map›Paper›PMID 21327160›Full record

ArticleTranscription

The Rad23 ubiquitin receptor, the proteasome and functional specificity in transcriptional control.

Staton L Wade, David T Auble

Open access · hybridAbstract read
In one paragraph

Article in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
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  7. The STI1-domain is a flexible alpha-helical fold with a hydrophobic groove.Protein science : a publication of the Protein Society · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Staton L WadeUniversity of Virginia Health System, Charlottesville, USA.
David T Auble
Charlottesville Medical Research · USUniversity of Virginia Health System · US

Funding

MOLECULAR ANALYSIS OF A YEAST TRANSCRIPTIONAL REGULATORR01GM055763 · NIGMS · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI AUBLE, DAVID T. · 1997 to 2021
$6.4M
NIGMS NIH HHS GM55763NIGMS NIH HHS R01 GM055763
6 · The paper itself

Abstract

The proteasome has been implicated in transcriptional control in a bewildering number of ways, and many questions remain about how functional selectivity is conferred to its action. Here we discuss transcriptional roles for the ubiquitin receptor Rad23 and posit that such receptors may be key players dictating proteasome transcriptional specificity.

Indexed as

Transcription, GeneticDNA-Binding ProteinsProteasome Endopeptidase ComplexSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsUbiquitinDNA-Binding ProteinsProteasome Endopeptidase ComplexRAD23 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsUbiquitin19S regulatory particleMig3proteasomeRad23transcriptionubiquitin

Identifiers

PMID21327160
PMCPMC3035185
OpenAlexW2011195625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.