Evidence map›Paper›PMID 21327125›Full record

ReviewBioengineered bugs

Bacillus thuringiensis: a genomics and proteomics perspective.

Mohamed A Ibrahim, Natalya Griko, Matthew Junker, Lee A Bulla

Open access · bronzeAbstract readReview
In one paragraph

Review in Bioengineered bugs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 243 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. A taste of one's own medicine:Frontiers in immunology · 2025
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Toxins · 2023
    Article
  12. Heliyon · 2023
    Article
  13. MultipleInternational journal of molecular sciences · 2023
    Article
  14. Article
  15. Cell death signaling inExperimental biology and medicine (Maywood, N.J.) · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Elucidating the genomic history of commercially usedFrontiers in cellular and infection microbiology · 2023
    Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohamed A IbrahimBiological Targets, Inc., Pilot Point, TX, USA.
Natalya Griko
Matthew Junker
Lee A Bulla
Kutztown University · USTarget (United States) · USThe University of Texas at Dallas · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacillus thuringiensis (Bt) is a unique bacterium in that it shares a common place with a number of chemical compounds which are used commercially to control insects important to agriculture and public health. Although other bacteria, including B. popilliae and B. sphaericus, are used as microbial insecticides, their spectrum of insecticidal activity is quite limited compared to Bt. Importantly, Bt is safe for humans and is the most widely used environmentally compatible biopesticide worldwide. Furthermore, insecticidal Bt genes have been incorporated into several major crops, rendering them insect resistant, and thus providing a model for genetic engineering in agriculture.This review highlights what the authors consider the most relevant issues and topics pertaining to the genomics and proteomics of Bt. At least one of the authors (L.A.B.) has spent most of his professional life studying different aspects of this bacterium with the goal in mind of determining the mechanism(s) by which it kills insects. The other authors have a much shorter experience with Bt but their intellect and personal insight have greatly enriched our understanding of what makes Bt distinctive in the microbial world. Obviously, there is personal interest and bias reflected in this article notwithstanding oversight of a number of published studies. This review contains some material not published elsewhere although several ideas and concepts were developed from a broad base of scientific literature up to 2010.

Indexed as

Amino Acid SequenceAnimalsBacillus thuringiensisBacillus thuringiensis ToxinsBacterial ProteinsBioengineeringCadherinsEndotoxinsGenetic EngineeringGenome, BacterialGenomicsHemolysin ProteinsInsecticide ResistanceModels, MolecularMolecular Sequence DataPest Control, BiologicalBacillus thuringiensis ToxinsBacterial ProteinsCadherinsEndotoxinsHemolysin Proteinsinsecticidal crystal protein, Bacillus ThuringiensisBacillus thuringiensiscadherin receptorscry toxinsparasporal crystalssporulationtoxin-receptor interaction

Identifiers

PMID21327125
PMCPMC3035146
OpenAlexW1991253147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.