Evidence map›Paper›PMID 21327113›Full record

ArticleGut microbes2010

Good fences make good neighbors: Gastrointestinal mucosal structure.

Hannah L Turner, Jerrold R Turner

Abstract read
In one paragraph

Article in Gut microbes, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. The enteric nervous system.Physiological reviews · 2023
    Review
  3. Role of CBAmerican journal of physiology. Gastrointestinal and liver physiology · 2022
    Article
  4. Molecular Alterations in the Stomach ofInternational journal of molecular sciences · 2020
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hannah L TurnerDepartment of Pathology; The University of Chicago; Chicago, IL USA.
Jerrold R Turner

Funding

ZO-1-MEDIATED PROTEIN INTERACTIONS: REGULATORS AND INTEGRATORS OF DIVERSE EPITHELIAL FUNCTIONS IN HEALTH AND DISEASER01DK061931 · NIDDK · UNIVERSITY OF CHICAGO · PI JERROLD R. TURNER · 2001 to 2026
$15.0M
Therapeutic targeting of protein interactions to reverse MLCK1-mediated intestinal barrier loss and ameliorate disease.R01DK068271 · NIDDK · UNIVERSITY OF CHICAGO · PI JERROLD R. TURNER · 2005 to 2026
$11.3M
Transcriptional Regulation of NHE-3 Isoform in Human IntestineP01DK067887 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI HECHT, GAIL A · 2006 to 2011
$4.9M
NIDDK NIH HHS P01 DK067887NIDDK NIH HHS R01 DK061931NIDDK NIH HHS R01 DK068271
6 · The paper itself

Abstract

The gastrointestinal lumen is home to over 400 species of microorganisms. The composition of this microbial community varies along the length of the gastrointestinal tract as a function of regional epithelial secretory activity as well as diet and other defined and undefined determinants. Improved understanding of the factors that impact luminal microbial populations and development of means to modulate gut microbes for therapeutic benefit hold great promise. The gastrointestinal epithelium, which regulates interactions between microbes and the mammalian host, is the topic of this review.

Identifiers

PMID21327113
PMCPMC3035135

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.