Evidence map›Paper›PMID 21327032›Full record

ArticleGut microbes2010

Mucin-bacterial interactions in the human oral cavity and digestive tract.

Muriel Derrien, Mark Wj van Passel, Jeroen Hb van de Bovenkamp, Raymond G Schipper, Willem M de Vos, Jan Dekker

Open access · bronzeAbstract read
In one paragraph

Article in Gut microbes, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 292 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
292citing papers in PubMed, 1 pooled it
22.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

292 citing papers in PubMed, 1 synthesis or guideline pooled it, 547 citations in OpenAlex.

  1. Pooled it
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  6. Article
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  11. Anaerobic riboflavin degradation by human gutJournal of bacteriology · 2026
    Article
  12. Article
  13. Biomolecules · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Anaerobic riboflavin degradation by human gutbioRxiv : the preprint server for biology · 2026
    Article
  18. Frontiers in microbiology · 2026
    Article
  19. Article
  20. Article

232 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Muriel DerrienTI Food and Nutrition; Wageningen University and Research Centre; Wageningen, The Netherlands.
Mark Wj van Passel
Jeroen Hb van de Bovenkamp
Raymond G Schipper
Willem M de Vos
Jan Dekker
Wageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucins are a family of heavily glycosylated proteins that are the major organic components of the mucus layer, the protective layer covering the epithelial cells in many human and animal organs, including the entire gastro-intestinal tract. Microbes that can associate with mucins benefit from this interaction since they can get available nutrients, experience physico-chemical protection and adhere, resulting in increased residence time. Mucin-degrading microorganisms, which often are found in consortia, have not been extensively characterized as mucins are high molecular weight glycoproteins that are hard to study because of their size, complexity and heterogeneity. The purpose of this review is to discuss how advances in mucus and mucin research, and insight in the microbial ecology promoted our understanding of mucin degradation. Recent insight is presented in mucin structure and organization, the microorganisms known to use mucin as growth substrate, with a specific attention on Akkermansia muciniphila, and the molecular basis of microbial mucin degradation owing to availability of genome sequences.

Identifiers

PMID21327032
PMCPMC3023607
OpenAlexW2020978031

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.