ArticleGhana medical journal2009
Plasma homocysteine as a risk factor for strokes in ghanaian adults.
Article in Ghana medical journal, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Development of a high-performing, cost-effective and inclusive Afrocentric predictive model for stroke: a meta-analysis approach.BMC neurology · 2025Pooled it
- Stroke in Ghana: A Situational Analysis.Stroke research and treatment · 2025Review
- Personalized Biomarkers and Neuropsychological Status Can Predict Post-Stroke Fatigue.Brain sciences · 2023Article
- Hyperhomocysteinemia and Ischemic Stroke: A Potential Dose-Response Association-A Systematic Review and Meta-analysis.TH open : companion journal to thrombosis and haemostasis · 2021Review
- Prevalence of hyperhomocysteinaemia, selected determinants and relation to hypertension severity in Northern-Nigerian hypertensives: the ABU homocysteine survey.Ghana medical journal · 2020Article
- Risk factors and assessment for cardiovascular disease among HIV-positive patients attending a Nigerian tertiary hospital.The Pan African medical journal · 2016Article
- The burden of stroke in Africa: a glance at the present and a glimpse into the future.Cardiovascular journal of AfricaReview
- Hyperhomocysteinemia and folate levels in normal healthy Nigerians living in Zaria: Subanalysis of ABU homocysteine cross-sectional survey.Annals of African medicineArticle
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStroke is an increasing problem in Ghana and the West African sub-region. New and modifiable risk factors for stroke have gained prominence in the last decade but have not been adequately researched in West Africa.
methodThis was a case-control study with plasma Homocysteine (Hcy) as an independent risk factor for stroke. 80 consecutive stroke patients with 80 age-sex matched controls were venesected in the fasting state for assay of Hcy and other biochemical parameters.
resultsMean Hcy level in stroke cases of 40.7 ± 9.5µmol/l was significantly higher than 16.8 ± 10.6µmol/l in controls [p<0.0001]. There was a significant association of hyperHcy with stroke [χ(2); p<0.0001]. OR of stroke calculated for quartiles of Hcy, demonstrated an increase in OR of 1.37 (25(th) percentile) to an OR of 3.80 (75(th) percentile).
conclusionsHcy was elevated in patients with stroke and should be considered as a modifiable risk factor for stroke in Ghanaian adults.
Indexed as
Identifiers
21326995PMC2956365What OpenQuestion holds
Registered trials
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