Evidence map›Paper›PMID 21326904›Full record

ReviewTranscription

CarD: a new RNA polymerase modulator in mycobacteria.

Christina L Stallings, Michael S Glickman

Open access · hybridAbstract readReview
In one paragraph

Review in Transcription. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. The calculation of transcript flux ratios reveals single regulatory mechanisms capable of activation and repression.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Christina L StallingsDepartment of Molecular Microbiology, Washington University, St. Louis, MO, USA. stallings@borcim.wustl.edu
Michael S Glickman
Kettering University · USWashington University in St. Louis · US

Funding

Novel pathway of DNA inter-strand crosslink repair in mycobacteriaR01AI064693 · NIAID · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Michael S Glickman, Stewart H Shuman · 2005 to 2026
$11.1M
NIAID NIH HHS R01 AI064693
6 · The paper itself

Abstract

Mycobacteria CarD is an essential RNAP binding protein that regulates many transcripts including rRNA. This article will review our present state of knowledge regarding CarD and compare the known functions of CarD with other RNAP binding proteins in E. coli, emphasizing how this information can guide future investigations.

Indexed as

Bacterial ProteinsCarrier ProteinsDNA-Directed RNA PolymerasesDNA ReplicationEscherichia coli ProteinsGenetic Complementation TestModels, GeneticMutationProtein BindingRNA, RibosomalTranscription FactorsTranscription, GeneticBacterial ProteinsCarrier ProteinsdksA protein, E coliDNA-Directed RNA PolymerasesEscherichia coli ProteinsRNA, RibosomalTranscription Factorstranscription repair coupling factor protein, BacteriaCarDDksADNA damagemycobacteriarRNAstringent responseTRFC

Identifiers

PMID21326904
PMCPMC3023641
OpenAlexW2207987040

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.