ArticleBioengineered bugs
Investigating the importance of charged residues in lantibiotics.
Article in Bioengineered bugs. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities.European journal of medicinal chemistry · 2016Article
- A general method for fluorescent labeling of the N-termini of lanthipeptides and its application to visualize their cellular localization.Journal of the American Chemical Society · 2013Article
- Extensive manipulation of caseicins A and B highlights the tolerance of these antimicrobial peptides to change.Applied and environmental microbiology · 2012Article
- Bioengineering: a bacteriocin perspective.BioengineeredArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lantibiotics are antimicrobial peptides which can have a broad spectrum activity against many Gram positive pathogens. Many of these peptides contain charged amino acids which may be of critical importance with respect to antimicrobial activity. We have recently carried out an in-depth bioengineering based investigation of the importance of charged residues in a representative two peptide lantibiotic, lacticin 3147, and here we discuss the significance of these findings in the context of other lantibiotics and cationic antimicrobial peptides.
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Registered trials
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