ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2011
Cancer risk related to low-dose ionizing radiation from cardiac imaging in patients after acute myocardial infarction.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 5 of them syntheses that pooled it.
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69 citing papers in PubMed, 5 syntheses or guidelines pooled it, 179 citations in OpenAlex.
- Cumulative radiation doses due to nuclear medicine examinations: a systematic review.The British journal of radiology · 2021Pooled it
- Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Rationale and Framework for the Monograph and Overview of Eligible Studies.Journal of the National Cancer Institute. Monographs · 2020Pooled it
- Evaluation of Confounding and Selection Bias in Epidemiological Studies of Populations Exposed to Low-Dose, High-Energy Photon Radiation.Journal of the National Cancer Institute. Monographs · 2020Pooled it
- Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Summary Bias Assessment and Meta-Analysis.Journal of the National Cancer Institute. Monographs · 2020Pooled it
- If it is published in the peer-reviewed literature, it must be true?Pediatric radiology · 2014Pooled it
- Development and validation of a patient-tailored dose regime in myocardial perfusion imaging using CZT-SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2014Trial
- A γ-radiation-responsive diselenide-core micelle for on-demand delivery of cannabidiol in the mitigation of acute radiation injury.Materials today. Bio · 2026Article
- SCAI/ASE/HRS/SIR/SVS Expert Consensus Statement on Enhanced Radiation Protection: Time for Mandatory and Urgent Action.Journal of the Society for Cardiovascular Angiography & Interventions · 2026Article
- Radiation safety in interventional nephrology.World journal of nephrology · 2025Review
- Radiation exposure in recurrent medical imaging: identifying drivers and high-risk populations.Frontiers in public health · 2025Review
- Consideration of Brain CT Imaging Standard for Mild Head Injuries.Neurologia medico-chirurgica · 2024Article
- Development and validation of the effective CNR analysis method for evaluating the contrast resolution of CT images.Physical and engineering sciences in medicine · 2024Article
- CanCHD Study of Hematopoietic Cancers in Children With and Without Genetic Syndromes.Journal of the American Heart Association · 2024Article
- Effects of joint screening for prostate, lung, colorectal, and ovarian cancer - results from a controlled trial.Frontiers in oncology · 2024Article
- Effect of cumulative radiation exposure from Coronary catheterization on lung cancer mortality.BMC cancer · 2023Article
- Clinical and Biological Predictors of Cancer Incidence and Mortality in Patients with Stable Coronary Artery Disease.International journal of molecular sciences · 2023Article
- Lympho-hematopoietic malignancies risk after exposure to low dose ionizing radiation during cardiac catheterization in childhood.European journal of epidemiology · 2023Article
- Modulation of Secondary Cancer Risks from Radiation Exposure by Sex, Age and Gonadal Hormone Status: Progress, Opportunities and Challenges.Journal of personalized medicine · 2022Review
- Human exposure to low dose ionizing radiation affects miR-21 and miR-625 expression levels.Molecular biology reports · 2022Article
- Electroanatomical Navigation to Minimize Contrast Medium or X-Rays During Stenting: Insights From an Experimental Model.JACC. Basic to translational science · 2022Article
9 more citing papers are in PubMed but not listed here.
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6 authors at 1 institution in 1 country.
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Abstract
backgroundPatients exposed to low-dose ionizing radiation from cardiac imaging and therapeutic procedures after acute myocardial infarction may be at increased risk of cancer.
methodsUsing an administrative database, we selected a cohort of patients who had an acute myocardial infarction between April 1996 and March 2006 and no history of cancer. We documented all cardiac imaging and therapeutic procedures involving low-dose ionizing radiation. The primary outcome was risk of cancer. Statistical analyses were performed using a time-dependent Cox model adjusted for age, sex and exposure to low-dose ionizing radiation from noncardiac imaging to account for work-up of cancer.
resultsOf the 82,861 patients included in the cohort, 77% underwent at least one cardiac imaging or therapeutic procedure involving low-dose ionizing radiation in the first year after acute myocardial infarction. The cumulative exposure to radiation from cardiac procedures was 5.3 milliSieverts (mSv) per patient-year, of which 84% occurred during the first year after acute myocardial infarction. A total of 12 020 incident cancers were diagnosed during the follow-up period. There was a dose-dependent relation between exposure to radiation from cardiac procedures and subsequent risk of cancer. For every 10 mSv of low-dose ionizing radiation, there was a 3% increase in the risk of age- and sex-adjusted cancer over a mean follow-up period of five years (hazard ratio 1.003 per milliSievert, 95% confidence interval 1.002-1.004).
interpretationExposure to low-dose ionizing radiation from cardiac imaging and therapeutic procedures after acute myocardial infarction is associated with an increased risk of cancer.
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