ArticleThe Journal of pediatrics2011
Genetic biomarkers of health-related quality of life in pediatric asthma.
Article in The Journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Genetic association of beta-lactams-induced hypersensitivity reactions: A systematic review of genome-wide evidence and meta-analysis of candidate genes.The World Allergy Organization journal · 2023Article
- Cytokine Genetic Variants and Health-Related Quality of Life in Crohn's Disease: An Exploratory Study.Biological research for nursing · 2019Article
- Expression of Salivary miR-203a-3p Was Related with Oral Health-Related Quality of Life in Healthy Volunteers.International journal of molecular sciences · 2017Article
- New perspectives on the regulation of type II inflammation in asthma.F1000Research · 2017Review
- Biological pathways and genetic mechanisms involved in social functioning.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013Article
- Cytokine gene polymorphism and graft-versus-host disease: a survey in Iranian bone marrow transplanted patients.Molecular biology reports · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectivesTo determine the relationship between single nucleotide polymorphisms in candidate genes associated with multiple asthma phenotypes and health-related quality of life (HRQOL). STUDY
designA cross-sectional study was conducted at a pediatric hospital in 275 school-aged children diagnosed with asthma and their caregivers. Genomic DNA was obtained from children, and caregivers completed a measure of their child's HRQOL. Analysis of variance was used to investigate the association between single nucleotide polymorphisms and HRQOL.
resultsChildren homozygous for the major variant at IL-4RA rs 1805010 had significantly better HRQOL than their counterparts. Significant associations with pulmonary function were not observed.
conclusionsGenes associated with asthma phenotype can be associated with HRQOL at least partly independent of pulmonary function.
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Registered trials
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