ArticleBMC evolutionary biology2011
Tracing the legacy of the early Hainan Islanders--a perspective from mitochondrial DNA.
Article in BMC evolutionary biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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23 citing papers in PubMed.
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- Diversity and distribution of mitochondrial DNA in non-Austronesian-speaking Taiwanese individuals.Human genome variation · 2023Article
- Tracing Bai-Yue Ancestry in Aboriginal Li People on Hainan Island.Molecular biology and evolution · 2022Article
- Genetic diversity and phylogenetic analysis of Chinese Han and Li ethnic populations from Hainan Island by 30 autosomal insertion/deletion polymorphisms.Forensic sciences research · 2022Article
- The evolutionary dynamics and epidemiological history of hepatitis C virus genotype 6, including unique strains from the Li community of Hainan Island, China.Virus evolution · 2022Article
- Positive relationships among aboveground biomass, tree species diversity, and urban greening management in tropical coastal city of Haikou.Ecology and evolution · 2021Article
- The forensic landscape and the population genetic analyses of Hainan Li based on massively parallel sequencing DNA profiling.International journal of legal medicine · 2021Article
- Genome-Wide Evidence for Complex Hybridization and Demographic History in a Group ofFrontiers in genetics · 2021Article
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- Carriers of human mitochondrial DNA macrohaplogroup M colonized India from southeastern Asia.BMC evolutionary biology · 2016Article
- Human settlement history between Sunda and Sahul: a focus on East Timor (Timor-Leste) and the Pleistocenic mtDNA diversity.BMC genomics · 2015Article
- An expanded taxonomy of hepatitis C virus genotype 6: Characterization of 22 new full-length viral genomes.Virology · 2015Article
- Carriers of Mitochondrial DNA Macrohaplogroup N Lineages Reached Australia around 50,000 Years Ago following a Northern Asian Route.PloS one · 2015Article
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4 authors.
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Abstract
backgroundHainan Island is located around the conjunction of East Asia and Southeast Asia, and during the Last Glacial Maximum (LGM) was connected with the mainland. This provided an opportunity for the colonization of Hainan Island by modern human in the Upper Pleistocene. Whether the ancient dispersal left any footprints in the contemporary gene pool of Hainan islanders is debatable.
resultsWe collected samples from 285 Li individuals and analyzed mitochondrial DNA (mtDNA) variations of hypervariable sequence I and II (HVS-I and II), as well as partial coding regions. By incorporating previously reported data, the phylogeny of Hainan islanders was reconstructed. We found that Hainan islanders showed a close relationship with the populations in mainland southern China, especially from Guangxi. Haplotype sharing analyses suggested that the recent gene flow from the mainland might play important roles in shaping the maternal pool of Hainan islanders. More importantly, haplogroups M12, M7e, and M7c1* might represent the genetic relics of the ancient population that populated this region; thus, 14 representative complete mtDNA genomes were further sequenced.
conclusionsThe detailed phylogeographic analyses of haplogroups M12, M7e, and M7c1* indicated that the early peopling of Hainan Island by modern human could be traced back to the early Holocene and/or even the late Upper Pleistocene, around 7-27 kya. These results correspond to both Y-chromosome and archaeological studies.
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