Trial reportAlcoholism, clinical and experimental research2011
Sleep following alcohol intoxication in healthy, young adults: effects of sex and family history of alcoholism.
Trial report in Alcoholism, clinical and experimental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it, 113 citations in OpenAlex.
- The impact of alcohol on breathing parameters during sleep: A systematic review and meta-analysis.Sleep medicine reviews · 2018Pooled it
- The role of baseline insomnia in moderating the hypnotic properties of quetiapine.Addictive behaviors · 2023Trial
- Effects of alcohol on sleep and nocturnal heart rate: Relationships to intoxication and morning-after effects.Alcoholism, clinical and experimental research · 2022Trial
- Effects of caffeinated vs. non-caffeinated alcoholic beverage on next-day hangover incidence and severity, perceived sleep quality, and alertness.Addictive behaviors · 2014Trial
- Associations of cannabis, alcohol, and tobacco use combinations with sleep health.Addictive behaviors reports · 2026Article
- Associations between sleep hygiene and secondary objective sleep parameters: moving beyond sleep duration.Journal of behavioral medicine · 2026Article
- Review
- Daily associations between sleep and alcohol use among veterans: Acute and cumulative effects.Addiction (Abingdon, England) · 2025Article
- Exploring the relationship between sleep patterns, alcohol and other substances consumption in young adults: Insights from wearables and Mobile surveys in the National Consortium on alcohol and NeuroDevelopment in adolescence (NCANDA) cohort.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025Article
- A narrative review on alcohol use in women: insight into the telescoping hypothesis from a biopsychosocial perspective.The American journal of drug and alcohol abuse · 2025Review
- Impact of Developmental Alcohol Exposure on Sleep Physiology.Advances in experimental medicine and biology · 2025Review
- Obesity and the accelerated decline in total sleep time increases the self-reported diagnoses of diabetes.Frontiers in endocrinology · 2025Article
- Assessing the daily association of sleep hygiene behaviours with sleep: A between and within persons approach.Journal of behavioral medicine · 2024Article
- Sleep Characteristics Among Children with a Parental History of Alcohol Use Disorder.Current addiction reports · 2024Review
- Sleep-Related Predictors of Risk for Alcohol Use and Related Problems in Adolescents and Young Adults.Alcohol research : current reviews · 2024Review
- Associations of Substance Use and Positive Coping Behaviors with Sleep Quality During the COVID-19 Pandemic.Frontiers in sleep · 2024Article
- Association between alcohol consumption and sleep difficulty in a nationwide Korean survey.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2024Article
- Sleep and circadian hygiene practices association with sleep quality among Brazilian adults.Sleep medicine: X · 2023Article
- The relationship between alcohol- and sleep-related traits: Results from polygenic risk score and Mendelian randomization analyses.Drug and alcohol dependence · 2023Article
- Sleep and substance use: Practice considerations for social workers.Journal of social work practice in the addictions · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThis study evaluated sex and family history of alcoholism as moderators of subjective ratings of sleepiness/sleep quality and polysomnography (PSG) following alcohol intoxication in healthy, young adults.
methodsNinety-three healthy adults [mean age 24.4 ± 2.7 years, 59 women, 29 subjects with a positive family history of alcoholism (FH+)] were recruited. After screening PSG, participants consumed alcohol (sex/weight adjusted dosing) to intoxication [peak breath alcohol concentration (BrAC) of 0.11 ± 0.01 g% for men and women] or matching placebo between 20:30 and 22:00 hours. Sleep was monitored using PSG between 23:00 and 07:00 hours. Participants completed the Stanford Sleepiness Scale and Karolinska Sleepiness Scale at bedtime and on awakening and a validated post-sleep questionnaire.
resultsFollowing alcohol, total sleep time, sleep efficiency, nighttime awakenings, and wake after sleep onset were more disrupted in women than men, with no differences by family history status. Alcohol reduced sleep onset latency, sleep efficiency, and rapid eye movement sleep while increasing wakefulness and slow wave sleep across the entire night compared with placebo. Alcohol also generally increased sleep consolidation in the first half of the night, but decreased it during the second half. Sleepiness ratings were higher following alcohol, particularly in women at bedtime. Morning sleep quality ratings were lower following alcohol than placebo.
conclusionsAlcohol intoxication increases subjective sleepiness and disrupts sleep objectively more in healthy women than in men, with no differences evident by family history of alcoholism status. Evaluating moderators of alcohol effects on sleep may provide insight into the role of sleep in problem drinking.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.