ArticleJournal of the American Chemical Society2011
Total synthesis of brevenal.
Article in Journal of the American Chemical Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- One-carbon homologation of alkenes.Nature · 2025Article
- Cyclization Strategies in Carbonyl-Olefin Metathesis: An Up-to-Date Review.Molecules (Basel, Switzerland) · 2024Review
- Carbonyl-Olefin Metathesis.Chemical reviews · 2021Review
- Marine Heterocyclic Compounds That Modulate Intracellular Calcium Signals: Chemistry and Synthesis Approaches.Marine drugs · 2021Review
- Article
- Sequential exo-mode oxacyclizations for the synthesis of the CD substructure of brevenal.The Journal of antibiotics · 2019Article
- Beyond olefins: new metathesis directions for synthesis.Chemical Society reviews · 2018Article
- Synthetic efforts towards the stereoselective synthesis of NF00659BBioorganic & medicinal chemistry letters · 2018Article
- Synthesis of the ABCDEF and FGHI ring system of yessotoxin and adriatoxin.The Journal of antibiotics · 2016Article
- Enantioselective total syntheses of FR901464 and spliceostatin A and evaluation of splicing activity of key derivatives.The Journal of organic chemistry · 2014Article
- Synthesis and reactivity of 4'-deoxypentenosyl disaccharides.The Journal of organic chemistry · 2014Article
- Recent progress in neuroactive marine natural products.Natural product reports · 2014Review
- Enantioselective syntheses of FR901464 and spliceostatin A: potent inhibitors of spliceosome.Organic letters · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
This Article describes the total synthesis of the marine ladder toxin brevenal utilizing a convergent synthetic strategy. Critical to the success of this work was the use of olefinic-ester cyclization reactions and the utilization of glycal epoxides as precursors to C-C and C-H bonds.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.