ArticleAntimicrobial agents and chemotherapy2011
Aspergillus fumigatus strains with mutations in the cyp51A gene do not always show phenotypic resistance to itraconazole, voriconazole, or posaconazole.
Article in Antimicrobial agents and chemotherapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed.
- Antifungal Susceptibility andMicroorganisms · 2026Article
- Article
- Genotype-Phenotype Relationships in Azole-ResistantJournal of fungi (Basel, Switzerland) · 2026Review
- Managing Breakthrough Fungal Infections in Hematologic Patients: Determinants and Practical Management from a Latin American Perspective on Behalf of INFOCUS LATAM-ISHAM Working Group.Microorganisms · 2026Review
- Global epidemiology of azole resistance inJAC-antimicrobial resistance · 2026Review
- Azole resistance screening inJournal of clinical microbiology · 2024Article
- Insights intoJournal of fungi (Basel, Switzerland) · 2024Article
- Triazole resistance inApplied and environmental microbiology · 2024Article
- Antifungal Susceptibility and Genotypic Analysis ofInfection and drug resistance · 2024Article
- Surveillance of Amphotericin B and Azole Resistance inJournal of fungi (Basel, Switzerland) · 2023Article
- Fungal Drug Response and Antimicrobial Resistance.Journal of fungi (Basel, Switzerland) · 2023Review
- Pulmonary Aspergillosis in Humboldt Penguins-Susceptibility Patterns and Molecular Epidemiology of Clinical and EnvironmentalAntibiotics (Basel, Switzerland) · 2023Article
- Article
- Triazole-Resistance in EnvironmentalJournal of fungi (Basel, Switzerland) · 2021Article
- First Investigative Study of Azole-ResistantInternational journal of environmental research and public health · 2021Article
- Antifungal Susceptibility Profiles and Drug Resistance Mechanisms of Clinical Lomentospora prolificans Isolates.Antimicrobial agents and chemotherapy · 2020Article
- A Simple Method To Detect Point Mutations in Aspergillus fumigatusAntimicrobial agents and chemotherapy · 2020Article
- Antifungal Susceptibility Tests and theMycobiology · 2020Article
- Article
- New Insights into the Cyp51 Contribution to Azole Resistance inAntimicrobial agents and chemotherapy · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We performed molecular identification of 98 Aspergillus fumigatus complex isolates with MICs of 1 to 4 μg/ml for itraconazole and searched for the presence of mutations in cyp51A. Most of the isolates (91%) belonged to A. fumigatus sensu stricto. We found 14 different mutations in nine isolates at codons different from G54, M220, G138, G448, and L98. We report new mutations at positions 165, 262, 479, and 497 (silent). The role of these mutations should be analyzed.
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