Evidence map›Paper›PMID 21321038›Full record

ArticlePediatrics2011

Ambulatory visit rates and antibiotic prescribing for children with pneumonia, 1994-2007.

Matthew P Kronman, Adam L Hersh, Rui Feng, Yuan-Shung Huang, Grace E Lee, Samir S Shah

Abstract readComparative Study
In one paragraph

Article in Pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
8.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 129 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Susceptibility to Childhood Pneumonia: A Genome-Wide Analysis.American journal of respiratory cell and molecular biology · 2017
    Trial
  4. Article
  5. Urine Metabolites of Suspected Community-Acquired Pneumonia.The Journal of infectious diseases · 2025
    Article
  6. Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Matthew P KronmanAbramson Research Center, Division of Infectious Diseases, The Children's Hospital of Philadelphia, 34th Street and Civic Center Blvd, Room 1202F, Philadelphia, PA 19104, USA. kronman@email.chop.edu
Adam L Hersh
Rui Feng
Yuan-Shung Huang
Grace E Lee
Samir S Shah
Children's Hospital of Philadelphia · USOffice of Infectious Diseases · USUniversity of California, San Francisco · USUniversity of Pennsylvania · US

Funding

Predicting adverse outcomes in children with community-acquired pneumoniaK01AI073729 · NIAID · CINCINNATI CHILDRENS HOSP MED CTR · PI SHAH, SAMIR SURESH · 2008 to 2012
$674k
NIAID NIH HHS K01 AI073729NIAID NIH HHS K01 AI73729
6 · The paper itself

Abstract

backgroundThe incidence of pediatric hospitalizations for community-acquired pneumonia (CAP) has declined after the widespread use of the heptavalent pneumococcal conjugate vaccine. The national incidence of outpatient visits for CAP, however, is not well established. Although no pediatric CAP treatment guidelines are available, current data support narrow-spectrum antibiotics as the first-line treatment for most patients with CAP.

objectiveTo estimate the incidence rates of outpatient CAP, examine time trends in antibiotics prescribed for CAP, and determine factors associated with broad-spectrum antibiotic prescribing for CAP. PATIENTS AND

methodsThe National Ambulatory and National Hospital Ambulatory Medical Care Surveys (1994-2007) were used to identify children aged 1 to 18 years with CAP using a validated algorithm. We determined age group-specific rates of outpatient CAP and examined trends in antibiotic prescribing for CAP. Data from 2006-2007 were used to study factors associated with broad-spectrum antibiotic prescribing.

resultsOverall, annual CAP visit rates ranged from 16.9 to 22.4 per 1000 population, with the highest rates occurring in children aged 1 to 5 years (range: 32.3-49.6 per 1000). Ambulatory CAP visit rates did not change between 1994 and 2007. Antibiotics commonly prescribed for CAP included macrolides (34% of patients overall), cephalosporins (22% overall), and penicillins (14% overall). Cephalosporin use increased significantly between 2000 and 2007 (P = .002). Increasing age, a visit to a nonemergency department office, and obtaining a radiograph or complete blood count were associated with broad-spectrum antibiotic prescribing.

conclusionsThe incidence of pediatric ambulatory CAP visits has not changed significantly between 1994 and 2007, despite the introduction of heptavalent pneumococcal conjugate vaccine in 2000. Broad-spectrum antibiotics, particularly macrolides, were frequently prescribed despite evidence that they provide little benefit over penicillins.

Indexed as

AdolescentAmbulatory CareAnti-Bacterial AgentsChildChild, PreschoolDrug PrescriptionsFemaleHumansInfantMaleOffice VisitsOutpatientsPneumoniaRetrospective StudiesUnited StatesAnti-Bacterial Agents

Identifiers

PMID21321038
PMCPMC3387910
OpenAlexW2145714100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.