ReviewBiochimica et biophysica acta2011
From sequence to function: Insights from natural variation in budding yeasts.
Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Disentangling the genetic bases of Saccharomyces cerevisiae nitrogen consumption and adaptation to low nitrogen environments in wine fermentation.Biological research · 2020Review
- Article
- Novel clinical and dual infection by Histoplasma capsulatum genotypes in HIV patients from Northeastern, Brazil.Scientific reports · 2019Article
- Accelerating structure-function mapping using the ViVa webtool to mine natural variation.Plant direct · 2019Article
- Differences in environmental stress response among yeasts is consistent with species-specific lifestyles.Molecular biology of the cell · 2016Article
- Population perspectives on functional genomic variation in yeast.Briefings in functional genomics · 2016Review
- Review
- Differential regulation of antagonistic pleiotropy in synthetic and natural populations suggests its role in adaptation.G3 (Bethesda, Md.) · 2015Article
- Genomic sequence diversity and population structure of Saccharomyces cerevisiae assessed by RAD-seq.G3 (Bethesda, Md.) · 2013Article
- High quality de novo sequencing and assembly of the Saccharomyces arboricolus genome.BMC genomics · 2013Article
- Conservation of replication timing reveals global and local regulation of replication origin activity.Genome research · 2012Article
- Advances in quantitative trait analysis in yeast.PLoS genetics · 2012Review
- A Geographically Diverse Collection of Schizosaccharomyces pombe Isolates Shows Limited Phenotypic Variation but Extensive Karyotypic Diversity.G3 (Bethesda, Md.) · 2011Article
- The Awesome Power of Yeast Evolutionary Genetics: New Genome Sequences and Strain Resources for the Saccharomyces sensu stricto Genus.G3 (Bethesda, Md.) · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
backgroundNatural variation offers a powerful approach for assigning function to DNA sequence-a pressing challenge in the age of high throughput sequencing technologies. SCOPE OF REVIEW: Here we review comparative genomic approaches that are bridging the sequence-function and genotype-phenotype gaps. Reverse genomic approaches aim to analyse sequence to assign function, whereas forward genomic approaches start from a phenotype and aim to identify the underlying genotype responsible. MAJOR
conclusionsComparative genomic approaches, pioneered in budding yeasts, have resulted in dramatic improvements in our understanding of the function of both genes and regulatory sequences. Analogous studies in other systems, including humans, demonstrate the ubiquity of comparative genomic approaches. Recently, forward genomic approaches, exploiting natural variation within yeast populations, have started to offer powerful insights into how genotype influences phenotype and even the ability to predict phenotypes. GENERAL SIGNIFICANCE: Comparative genomic experiments are defining the fundamental rules that govern complex traits in natural populations from yeast to humans. This article is part of a Special Issue entitled Systems Biology of Microorganisms.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.