ReviewBioanalysis2011
From pixel to voxel: a deeper view of biological tissue by 3D mass spectral imaging.
Review in Bioanalysis, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Matrix-Assisted Laser Desorption/Ionization Imaging Mass Spectrometry.Nature reviews. Methods primers · 2026Article
- ToF-SIMS 3D imaging unveils important insights on the cellular microenvironment during biomineralization of gold nanostructures.Scientific reports · 2020Article
- 3D chemical imaging of the brain using quantitative IR spectro-microscopy.Chemical science · 2018Article
- Mass spectrometric analysis of spatio-temporal dynamics of crustacean neuropeptides.Biochimica et biophysica acta · 2015Review
- Mass spectrometry of natural products: current, emerging and future technologies.Natural product reports · 2014Review
- Challenges and recent advances in mass spectrometric imaging of neurotransmitters.Bioanalysis · 2014Review
- Visualizing neurotransmitters and metabolites in the central nervous system by high resolution and high accuracy mass spectrometric imaging.ACS chemical neuroscience · 2013Article
- Qualitative and quantitative mass spectrometry imaging of drugs and metabolites.Advanced drug delivery reviews · 2013Review
- Function-driven discovery of neuropeptides with mass spectrometry-based tools.Protein and peptide letters · 2013Review
- A vision for better health: mass spectrometry imaging for clinical diagnostics.Clinica chimica acta; international journal of clinical chemistry · 2013Review
- Analysis of tissue specimens by matrix-assisted laser desorption/ionization imaging mass spectrometry in biological and clinical research.Chemical reviews · 2013Review
- Mapping of neuropeptides in the crustacean stomatogastric nervous system by imaging mass spectrometry.Journal of the American Society for Mass Spectrometry · 2013Article
- Probing neuropeptide signaling at the organ and cellular domains via imaging mass spectrometry.Journal of proteomics · 2012Review
- 3D imaging by mass spectrometry: a new frontier.Analytical chemistry · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Three dimensional mass spectral imaging (3D MSI) is an exciting field that grants the ability to study a broad mass range of molecular species ranging from small molecules to large proteins by creating lateral and vertical distribution maps of select compounds. Although the general premise behind 3D MSI is simple, factors such as choice of ionization method, sample handling, software considerations and many others must be taken into account for the successful design of a 3D MSI experiment. This review provides a brief overview of ionization methods, sample preparation, software types and technological advancements driving 3D MSI research of a wide range of low- to high-mass analytes. Future perspectives in this field are also provided to conclude that the outlook for 3D MSI is positive and promises ever-growing applications in the biomedical field with continuous developments of this powerful analytical tool.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.