ArticleDialogues in clinical neuroscience2010
Neurocircuitry of emotion and cognition in alcoholism: contributions from white matter fiber tractography.
Article in Dialogues in clinical neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- A coordinate-based meta-analysis of white matter alterations in patients with alcohol use disorder.Translational psychiatry · 2022Pooled it
- Double-blind, randomized placebo-controlled clinical trial of benfotiamine for severe alcohol dependence.Drug and alcohol dependence · 2013Trial
- The role of the subcortical structures in subthreshold depression: evidence from static and dynamic functional connectivity.Brain structure & function · 2026Article
- Role of deep brain stimulation (DBS) in addiction disorders.Surgical neurology international · 2023Review
- From Emotional (Dys)Regulation to Internet Addiction: A Mediation Model of Problematic Social Media Use among Italian Young Adults.Journal of clinical medicine · 2021Article
- Korsakoff syndrome: An overlook (Review).Experimental and therapeutic medicine · 2021Review
- A biological framework for emotional dysregulation in alcohol misuse: from gut to brain.Molecular psychiatry · 2021Review
- The impact of emotional face stimuli on working memory performance among men and women with alcohol use disorder.Addictive behaviors · 2021Article
- Binge drinking is associated with altered resting state functional connectivity of reward-salience and top down control networks.Brain imaging and behavior · 2020Article
- Substance abuse and white matter: Findings, limitations, and future of diffusion tensor imaging research.Drug and alcohol dependence · 2019Review
- Aberrations of anterior insular cortex functional connectivity in nontreatment-seeking alcoholics.Psychiatry research. Neuroimaging · 2019Article
- Towards a Dynamic Exploration of Vision, Cognition and Emotion in Alcohol-Use Disorders.Current neuropharmacology · 2019Review
- Molecular Neuropathology of Astrocytes and Oligodendrocytes in Alcohol Use Disorders.Frontiers in molecular neuroscience · 2018Review
- MicroRNA-21: Expression in oligodendrocytes and correlation with low myelin mRNAs in depression and alcoholism.Progress in neuro-psychopharmacology & biological psychiatry · 2017Article
- Alcoholism and sexual dimorphism in the middle longitudinal fascicle: a pilot study.Brain imaging and behavior · 2017Article
- The neurobiology of addiction: the perspective from magnetic resonance imaging present and future.Addiction (Abingdon, England) · 2017Review
- The Resting Brain of Alcoholics.Cerebral cortex (New York, N.Y. : 1991) · 2015Article
- Social cognition deficits and associations with drinking history in alcoholic men and women.Alcoholism, clinical and experimental research · 2014Article
- The effects of acute alcohol administration on the human brain: insights from neuroimaging.Neuropharmacology · 2014Review
- Reduced left executive control network functional connectivity is associated with alcohol use disorders.Alcoholism, clinical and experimental research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
Abstract
Chronic alcoholism is characterized by impaired control over emotionally motivated actions towards alcohol use. Neuropathologically, it is associated with widespread brain structural compromise marked by gray matter shrinkage, ventricular enlargement, and white matter degradation. The extent to which cortical damage itself or cortical disconnection by white matter fiber pathway disruption contribute to deficits in emotion, cognition, and behavior can be investigated with in vivo structural neuroimaging and diffusion tensor imaging (DTI)-based quantitative fiber tracking. Tractography in alcoholism has revealed abnormalities in selective white matter fiber bundles involving limbic fiber tracts (fornix and cingulum) that connect cortico-limbic-striatal nodes of emotion and reward circuits. Studies documenting brain-behavior relationships support the role of alcoholism-related white matter fiber degradation as a substrate of clinical impairment. An understanding of the role of cortico-limbic fiber degradation in emotional dysregulation in alcoholism is now emerging.
Indexed as
Identifiers
21319499PMC3181985W1667987545What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.