Evidence map›Paper›PMID 21319277›Full record

ArticleBirth defects research. Part A, Clinical and molecular teratology2011

Fetal genetic risk of isolated cleft lip only versus isolated cleft lip and palate: a subphenotype analysis using two population-based studies of orofacial clefts in Scandinavia.

Astanand Jugessur, Min Shi, Håkon Kristian Gjessing, Rolv Terje Lie, Allen James Wilcox, Clarice Ring Weinberg, Kaare Christensen, Abee Lowman Boyles, Sandra Daack-Hirsch, Truc Trung Nguyen and 3 more

Abstract read
In one paragraph

Article in Birth defects research. Part A, Clinical and molecular teratology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Trial
  2. Comprehensive analysis ofmedRxiv : the preprint server for health sciences · 2026
    Article
  3. Article
  4. Article
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  11. Article
  12. Article
  13. Microtia: epidemiology and genetics.American journal of medical genetics. Part A · 2012
    Review
  14. Genetics of nonsyndromic orofacial clefts.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2012
    Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Astanand JugessurDivision of Epidemiology, Norwegian Institute of Public Health, Nydalen, Oslo, Norway. astanand.jugessur@fhi.no
Min Shi
Håkon Kristian Gjessing
Rolv Terje Lie
Allen James Wilcox
Clarice Ring Weinberg
Kaare Christensen
Abee Lowman Boyles
Sandra Daack-Hirsch
Truc Trung Nguyen
Lene Christiansen
Andrew Carl Lidral
Jeffrey Clark Murray

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Brandi Janssen · 1990 to 2026
$40.5M
THERMAL ASSEMBLY OF MINERAL/COLLAGEN BIOMATERIALSP60DE013076 · NIDCR · UNIVERSITY OF IOWA · PI MURRAY, JEFFREY C · 1999 to 2003
$8.4M
Molecular Genetic Epidemiology of Cleft Lip and PalateR37DE008559 · NIDCR · UNIVERSITY OF IOWA · PI MURRAY, JEFFREY C · 2004 to 2013
$6.8M
Statistical Methods For Genetic EpidemiologyZIAES040007 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WEINBERG, CLARICE · 2009 to 2025
$6.5M
NIEHS Statistical Consulting ServiceZIAES045005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDDADA, SHYAMAL · 2009 to 2011
$2.8M
Environmental And Genetic Causes Of Birth DefectsZIAES049027 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILCOX, ALLEN J · 2009 to 2020
$2.6M
GENE-ENVIRONMENT INTERACTION IN FACIAL CLEFTSR01DE011948 · NIDCR · UNIVERSITY OF SOUTHERN DENMARK · PI CHRISTENSEN, KAARE · 1998 to 2006
$1.8M
GENOTYPING FOR LOCATING HUMAN DISEASE GENESN01HG065403 · NHGRI · JOHNS HOPKINS UNIVERSITY · PI VALLE, DAVID L · 1996 to 2000
$1.7M
MOLECULAR GENETIC EPIDEMIOLOGY OF CLEFT LIP AND PALATER01DE008559 · NIDCR · UNIVERSITY OF IOWA · PI MURRAY, JEFFREY C · 1988 to 2003
$1.5M
STATISTICAL METHODS IN REPRODUCTIVE EPIDEMIOLOGYZ01ES040007 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WEINBERG, CLARICE · 1997 to 2008
$512k
Intramural NIH HHS Z01 ES040007Intramural NIH HHS ZIA ES040007NHGRI NIH HHS N01 HG065403NIDCR NIH HHS DE08559NIDCR NIH HHS DE11948NIDCR NIH HHS P60 DE013076NIDCR NIH HHS P60 DE13076NIDCR NIH HHS R01 DE008559NIDCR NIH HHS R01 DE011948NIDCR NIH HHS R01 DE-11948-04NIDCR NIH HHS R37 DE008559NIEHS NIH HHS P30 ES005605NIEHS NIH HHS P30 ES05605
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Association StudiesGenetic Predisposition to DiseaseCleft LipCleft PalateConnexin 43FemaleFibroblast Growth FactorsHumansInterferon Regulatory FactorsMalePhenotypePolymorphism, Single NucleotideScandinavian and Nordic CountriesVinculinConnexin 43FGF12 protein, humanFibroblast Growth FactorsInterferon Regulatory FactorsIRF6 protein, humanVCL protein, humanVinculin

Identifiers

PMID21319277
PMCPMC3407039

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.