Evidence map›Paper›PMID 21318016›Full record

ArticleInternational journal of environmental research and public health2011

Four polygamous families with congenital birth defects from Fallujah, Iraq.

Samira Alaani, Mozhgan Savabieasfahani, Mohammad Tafash, Paola Manduca

Abstract read
In one paragraph

Article in International journal of environmental research and public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Metal contamination and the epidemic of congenital birth defects in Iraqi cities.Bulletin of environmental contamination and toxicology · 2012
    Article
  9. Birth defects in Gaza: prevalence, types, familiarity and correlation with environmental factors.International journal of environmental research and public health · 2012
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samira AlaaniFallujah General Hospital, Althubbadh District, Fallujah, 00964, Iraq. samiraalaani@hotmail.com
Mozhgan Savabieasfahani
Mohammad Tafash
Paola Manduca

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since 2003, congenital malformations have increased to account for 15% of all births in Fallujah, Iraq. Congenital heart defects have the highest incidence, followed by neural tube defects. Similar birth defects were reported in other populations exposed to war contaminants. While the causes of increased prevalence of birth defects are under investigation, we opted to release this communication to contribute to exploration of these issues. By using a questionnaire, containing residential history and activities that may have led to exposure to war contaminants, retrospective reproductive history of four polygamous Fallujah families were documented. Our findings point to sporadic, untargeted events, with different phenotypes in each family and increased recurrence. The prevalence of familial birth defects after 2003 highlights the relevance of epigenetic mechanisms and offers insights to focus research, with the aim of reducing further damage to people's health.

Indexed as

AdultCongenital AbnormalitiesEnvironmental ExposureEpigenesis, GeneticFemaleHumansInfant, NewbornIraqIraq War, 2003-2011MaleMarriageMetals, HeavyMiddle AgedPhenotypeRetrospective StudiesSurveys and QuestionnairesMetals, HeavyTeratogensbirth defectsepigeneticsIraqwar contaminants

Identifiers

PMID21318016
PMCPMC3037062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.