ArticleHormones and behavior2011
Chronotype changes during puberty depend on gonadal hormones in the slow-developing rodent, Octodon degus.
Article in Hormones and behavior, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 42 citations in OpenAlex.
- Inadequate sleep is a risk factor for pediatric hypertension: the pathophysiologic and socioeconomic correlates.Pediatric research · 2026Review
- Chronotype, cognitive outcomes, and neural dynamics: recent evidence and potential mechanisms with implications for perioperative period.Frontiers in neuroscience · 2025Review
- Sex differences in daily timekeeping and circadian clock circuits.Seminars in cell & developmental biology · 2022Review
- Chronotype at the beginning of secondary school and school timing are both associated with chronotype development during adolescence.Scientific reports · 2022Article
- Central precocious puberty during COVID-19 pandemic and sleep disturbance: an exploratory study.Italian journal of pediatrics · 2022Article
- Juvenile hormone affects the development and strength of circadian rhythms in young bumble beeNeurobiology of sleep and circadian rhythms · 2020Article
- Pregnancy Induces an Earlier Chronotype in Both Mice and Women.Journal of biological rhythms · 2019Article
- Sleep Timing in Patients with Precocious and Delayed Pubertal Development.Clocks & sleep · 2019Article
- Article
- Suprachiasmatic nucleus as the site of androgen action on circadian rhythms.Hormones and behavior · 2015Article
- Chronotype ontogeny related to gender.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2014Article
- Sex differences in behavioral circadian rhythms in laboratory rodents.Frontiers in endocrinology · 2014Review
- Gonadal steroid modulation of sleep and wakefulness in male and female rats is sexually differentiated and neonatally organized by steroid exposure.Endocrinology · 2014Article
- Adolescent sleep patterns in humans and laboratory animals.Hormones and behavior · 2013Review
- The neuroendocrine control of the circadian system: adolescent chronotype.Frontiers in neuroendocrinology · 2012Review
- Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
During puberty, human adolescents develop a later chronotype, exhibiting a delay in the timing of rest and activity as well as other daily physiological rhythms. The purpose of this study was to determine whether similar changes in chronotype occur during puberty in a laboratory rodent species, and, if so, to determine whether they are due to pubertal hormones acting on the circadian timekeeping system. To test this hypothesis, we carefully tracked daily activity rhythms across puberty in the slow-developing rodent Octodon degus. We confirmed that male degus showed a large reorganization of activity rhythms that correlated with secondary sex development during puberty, including a loss of bimodality and a 3-5 h phase-advance. Similar to humans, this circadian reorganization showed distinct sex differences, with females showing little change during puberty in two separate experiments. Prepubertal gonadectomy (GDX) eliminated the changes, whereas SHAM gonadectomy had little impact. Therefore, gonadal hormones are likely to play a role in pubertal changes in chronotype in this rodent species. Using evidence from a variety of species, including our recent studies in the rat, we conclude that chronotype changes during puberty are a well-demonstrated phenomenon in mammals.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.