ArticleEnvironmental research2011
Distribution of toenail selenium levels in young adult Caucasians and African Americans in the United States: the CARDIA Trace Element Study.
Article in Environmental research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Genome-wide association study of selenium concentrations.Human molecular genetics · 2015Pooled it
- Association between toenail scandium concentrations and incidence of hypertension among American young adults: 28 years of follow-up.Environmental research · 2026Article
- Contributions of selenoproteins to breast cancer etiology and racial disparity.Cancer causes & control : CCC · 2026Article
- Scientific opinion on the tolerable upper intake level for selenium.EFSA journal. European Food Safety Authority · 2023Article
- SELENOF is a new tumor suppressor in breast cancer.Oncogene · 2022Article
- Loss of SELENOF Induces the Transformed Phenotype in Human Immortalized Prostate Epithelial Cells.International journal of molecular sciences · 2021Article
- Dietary Selenium Requirement for the Prevention of Glucose Intolerance and Insulin Resistance in Middle-Aged Mice.The Journal of nutrition · 2021Article
- The Interaction between Dietary Selenium Intake and Genetics in Determining Cancer Risk and Outcome.Nutrients · 2020Review
- Toenails as biomarker of exposure to essential trace metals: A review.Environmental research · 2019Review
- The content of essential and toxic elements in the hair of the mane of the trotter horses depending on their speed.Environmental science and pollution research international · 2018Article
- Trace element contents in toenails are related to regular physical activity in older adults.PloS one · 2017Article
- Features of selenium metabolism in humans living under the conditions of North European Russia.International archives of occupational and environmental health · 2014Article
- Selenium toxicity from a misformulated dietary supplement, adverse health effects, and the temporal response in the nail biologic monitor.Nutrients · 2013Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
backgroundData on selenium (Se) levels in American young adults, especially in African Americans, are lacking.
objectiveThis study presented toenail Se distributions in American young adults of both genders, including both Caucasians and African Americans; and explored potential predictors of toenail Se levels. DATA AND
methodsData from the Coronary Artery Risk Development in Young Adults study among 4252 American young adults, aged 20-32 in 1987 was used to examine toenail Se levels by instrumental neutron-activation analysis. The distribution of Se levels was described and multivariable linear regression was used to examine potential modifiers of toenail Se concentration within ethnicity-gender subgroups.
resultsThe geometric mean of toenail Se in this cohort was 0.844 μg/g (95% CI, 0.840-0.849 μg/g) and the median was 0.837 μg/g (95% CI, 0.833-0.844 μg/g). Median levels from lowest to highest quintile were 0.691, 0.774, 0.838, 0.913 and 1.037 μg/g. Se levels varied geographically, and were generally in accordance with its concentrations in local soil. Males, African Americans, current smokers, heavy drinkers and less educated participants were more likely to have low Se levels.
conclusionThis study suggests that toenail Se levels vary geographically depending on soil Se concentrations. In addition to gender, ethnicity and education level, smoking status and alcohol consumption are two important indicators of Se status since they are modifiable lifestyle factors. Findings from this study might aid public health professionals in identifying people at relatively high or low Se levels, so that chronic disease prevention efforts can be directed toward these subgroups.
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Registered trials
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