ArticleJournal of theoretical biology2011
Slow variable dominance and phase resetting in phantom bursting.
Article in Journal of theoretical biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Emergent hypernetworks in weakly coupled oscillators.Nature communications · 2022Article
- Quantifying the relative contributions of divisive and subtractive feedback to rhythm generation.PLoS computational biology · 2011Article
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5 authors.
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Abstract
Bursting oscillations are common in neurons and endocrine cells. One type of bursting model with two slow variables has been called 'phantom bursting' since the burst period is a blend of the time constants of the slow variables. A phantom bursting model can produce bursting with a wide range of periods: fast (short period), medium, and slow (long period). We describe a measure, which we call the 'dominance factor', of the relative contributions of the two slow variables to the bursting produced by a simple phantom bursting model. Using this tool, we demonstrate how the control of different phases of the burst can be shifted from one slow variable to another by changing a model parameter. We then show that the dominance curves obtained as a parameter is varied can be useful in making predictions about the resetting properties of the model cells. Finally, we demonstrate two mechanisms by which phase-independent resetting of a burst can be achieved, as has been shown to occur in the electrical activity of pancreatic islets.
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