ArticleJournal of insect physiology2011
Function and immuno-localization of aquaporins in the Antarctic midge Belgica antarctica.
Article in Journal of insect physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 41 citations in OpenAlex.
- Discovery of an aquaporin (CrAQP2) in the freshwater larval midge,Current research in insect science · 2026Article
- Genome-Wide Identification and Expression Analysis of the Aquaporin Gene Family in the Qinghai Toad-Headed Agama (Biology · 2025Article
- Protein localization of aquaporins in the adult female disease vector mosquito,Frontiers in insect science · 2024Article
- Article
- Identification, Expression Patterns and RNA Interference of Aquaporins inFrontiers in physiology · 2019Article
- Identification and Functional Analysis of the First Aquaporin from Striped Stem Borer,Frontiers in physiology · 2018Article
- The physiological role of fat body and muscle tissues in response to cold stress in the tropical cockroach Gromphadorhina coquereliana.PloS one · 2017Article
- Insect glycerol transporters evolved by functional co-option and gene replacement.Nature communications · 2015Article
- Aquaporins in the honeybee crop--a new function for an old organ.Protoplasma · 2014Article
- Emerging roles of aquaporins in relation to the physiology of blood-feeding arthropods.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2014Review
- Aquaporins are critical for provision of water during lactation and intrauterine progeny hydration to maintain tsetse fly reproductive success.PLoS neglected tropical diseases · 2014Article
- Expression of genes involved in energy mobilization and osmoprotectant synthesis during thermal and dehydration stress in the Antarctic midge, Belgica antarctica.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2013Article
- Gene expression changes governing extreme dehydration tolerance in an Antarctic insect.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Water homeostasis: evolutionary medicine.Transactions of the American Clinical and Climatological Association · 2012Review
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 1 country.
Funding
Abstract
Aquaporin (AQP) water channel proteins play key roles in water movement across cell membranes. Extending previous reports of cryoprotective functions in insects, this study examines roles of AQPs in response to dehydration, rehydration, and freezing, and their distribution in specific tissues of the Antarctic midge, Belgica antarctica (Diptera, Chironomidae). When AQPs were blocked using mercuric chloride, tissue dehydration tolerance increased in response to hypertonic challenge, and susceptibility to overhydration decreased in a hypotonic solution. Blocking AQPs decreased the ability of tissues from the midgut and Malpighian tubules to tolerate freezing, but only minimal changes were noted in cellular viability of the fat body. Immuno-localization revealed that a DRIP-like protein (a Drosophila aquaporin), AQP2- and AQP3 (aquaglyceroporin)-like proteins were present in most larval tissues. DRIP- and AQP2-like proteins were also present in the gut of adult midges, but AQP4-like protein was not detectable in any tissues we examined. Western blotting indicated that larval AQP2-like protein levels were increased in response to dehydration, rehydration and freezing, whereas, in adults DRIP-, AQP2-, and AQP3-like proteins were elevated by dehydration. These results imply a vital role for aquaporin/aquaglyceroporins in water relations and freezing tolerance in B. antarctica.
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Registered trials
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