Evidence map›Paper›PMID 21315067›Full record

ArticleEuropean journal of pharmacology2011

Utilize conjugated melanotropins for the earlier diagnosis and treatment of melanoma.

Minying Cai, Zhonglin Liu, Hongchang Qu, Helen Fan, Zhiping Zheng, Victor J Hruby

Abstract read
In one paragraph

Article in European journal of pharmacology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Minying CaiDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, AZ 85721, USA.
Zhonglin Liu
Hongchang Qu
Helen Fan
Zhiping Zheng
Victor J Hruby
University of Arizona · US

Funding

NOVEL NON-PEPTIDE OPIOID LIGANDS FOR PAINR01DA013449 · NIDA · UNIVERSITY OF ARIZONA · PI HRUBY, VICTOR J · 2000 to 2015
$6.8M
Multimeric Ligands for Targeting of MelanomaR01CA097360 · NCI · UNIVERSITY OF ARIZONA · PI HRUBY, VICTOR J, MORSE, DAVID L · 2003 to 2012
$5.5M
PEPTIDE HORMONE STRUCTURE &FUNCTIONR01DK017420 · NIDDK · UNIVERSITY OF ARIZONA · PI HRUBY, VICTOR J · 1986 to 2010
$2.8M
NCI NIH HHS R01 CA097360NIDA NIH HHS R01 DA013449NIDDK NIH HHS R01 DK017420
6 · The paper itself

Abstract

Peptides serve as effective drugs and contrast agents in the clinic today. However the inherent drawbacks of peptide structures can limit their efficacy as drugs. To overcome this we have been developing new methods to create 'tailor-made' peptides and peptide mimetics with improved pharmacological and physical properties. In this work we introduce novel peptide and small molecule conjugated molecules for earlier diagnosis and treatment of melanoma.

Indexed as

Early Detection of CancerAmino Acid SequenceAnimalsCell Line, TumorHEK293 CellsHumansMelanocyte-Stimulating HormonesMelanomaMiceReceptor, Melanocortin, Type 1Xenograft Model Antitumor AssaysMelanocyte-Stimulating HormonesReceptor, Melanocortin, Type 1

Identifiers

PMID21315067
PMCPMC3095766
OpenAlexW2038084025

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.