ArticleEuropean archives of psychiatry and clinical neuroscience2011
Sleep homeostasis in alcohol-dependent, depressed and healthy control men.
Article in European archives of psychiatry and clinical neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Sleep and mental disorders: A meta-analysis of polysomnographic research.Psychological bulletin · 2016Pooled it
- Review
- Review
- Article
- Optimizing computation of overnight decline in delta power: Evidence for slower rate of decline in delta power in insomnia patients.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2021Article
- How Psychoactive Drugs and the Circadian Clock Are Enlightening One Another.Advances in experimental medicine and biology · 2021Article
- Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.Neuropsychopharmacology reports · 2020Review
- Preliminary Evidence That Real World Sleep Timing and Duration are Associated With Laboratory-Assessed Alcohol Response.Alcoholism, clinical and experimental research · 2019Article
- Alcohol Consumption as a Moderator of Anxiety and Sleep Quality.The journal of nursing research : JNR · 2019Article
- Neurophysiological correlates of suicidal ideation in major depressive disorder: Hyperarousal during sleep.Journal of affective disorders · 2017Article
- Has adult sleep duration declined over the last 50+ years?Sleep medicine reviews · 2016Review
- Alcohol disrupts sleep homeostasis.Alcohol (Fayetteville, N.Y.) · 2015Review
- Sleep and substance use disorders: an update.Current psychiatry reports · 2014Review
- Alcohol and the sleeping brain.Handbook of clinical neurology · 2014Review
- Disturbed dreaming and sleep quality: altered sleep architecture in subjects with frequent nightmares.European archives of psychiatry and clinical neuroscience · 2012Article
- Sex-related differences in sleep slow wave activity in major depressive disorder: a high-density EEG investigation.BMC psychiatry · 2012Article
- Dissipation of sleep pressure is stable across adolescence.Neuroscience · 2012Article
- Overnight changes in waking auditory evoked potential amplitude reflect altered sleep homeostasis in major depression.Acta psychiatrica Scandinavica · 2012Article
- Article
- The influence of emerging low mood symptoms on sleep in children: a pilot study.Nature and science of sleep · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Visually scored and power spectral analyses (PSA) of polysomnography (PSG) recordings reveal abnormalities in alcohol dependence (AD) and major depressive disorder (MDD), including deficiencies in slow wave activity (SWA) during non-rapid eye movement (NREM) sleep. SWA parameters reflect the integrity of the homeostatic sleep drive, which have not been compared in those with AD or MDD. Ten men with AD were compared with 10 men with MDD and 10 healthy controls (HCs), all aged 20-40 years. They maintained an 11 pm to 6 am sleep schedule for 5-7 days, followed by 3 consecutive nights of PSG in the laboratory: night 1 for adaptation/screening; night 2 for baseline recordings; and night 3 as the challenge night, delaying sleep until 2 am. SWA was quantified with PSA across 4 NREM periods. Men with AD generated the least SWA at baseline. In response to sleep delay, HC men showed the expected SWA enhancement and a sharper exponential decline across NREM periods. Both the MDD and the AD groups showed a significantly blunted SWA response to sleep delay. Men with MDD had the least SWA in the first NREM period (impaired accumulation of sleep drive), whereas men with AD had the slowest SWA decay rate (impaired dissipation of sleep drive). These results suggest that both SWA generation and its homeostatic regulation are impaired in men with either AD or MDD. Finding interventions that selectively improve these different components of sleep homeostasis should be a goal of treatment for AD and MDD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.