Evidence map›Paper›PMID 21310769›Full record

ReviewVascular medicine (London, England)2011

Emerging diagnostic and therapeutic molecular imaging applications in vascular disease.

Luis H Eraso, Muredach P Reilly, Chandra Sehgal, Emile R Mohler

Erratum issuedAbstract readReview
In one paragraph

Review in Vascular medicine (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Targeting and therapeutic peptides in nanomedicine for atherosclerosis.Experimental biology and medicine (Maywood, N.J.) · 2016
    Review
  3. Review
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

4 authors.

Luis H ErasoCardiovascular Division, Vascular Medicine Section, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA. Luis.Eraso@uphs.upenn.edu
Muredach P Reilly
Chandra Sehgal
Emile R Mohler

Funding

Research career training in vascular medicineK12HL083772 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI MOHLER, EMILE R. · 2007 to 2012
$3.1M
NHLBI NIH HHS K12 HL083772NHLBI NIH HHS K12-HL083772
6 · The paper itself

Abstract

Assessment of vascular disease has evolved from mere indirect and direct measurements of luminal stenosis to sophisticated imaging methods to depict millimeter structural changes of the vasculature. In the near future, the emergence of multimodal molecular imaging strategies may enable robust therapeutic and diagnostic ('theragnostic') approaches to vascular diseases that comprehensively consider structural, functional, biological and genomic characteristics of the disease in individualized risk assessment, early diagnosis and delivery of targeted interventions.This review presents a summary of recent preclinical and clinical developments in molecular imaging and theragnostic applications covering diverse atherosclerosis events such as endothelial activation, macrophage inflammatory activity, plaque neovascularization and arterial thrombosis. The main focus is on molecular targets designed for imaging platforms commonly used in clinical medicine including magnetic resonance, computed tomography and positron emission tomography. A special emphasis is given to vascular ultrasound applications, considering the important role this imaging platform plays in the clinical and research practice of the vascular medicine specialty.

Indexed as

AtherosclerosisDrug Delivery SystemsFerrosoferric OxideHumansMolecular ImagingNeovascularization, PathologicPlaque, AtheroscleroticRadiopharmaceuticalsThrombolytic TherapyThrombosisUltrasonographyVascular DiseasesFerrosoferric OxideRadiopharmaceuticals

Identifiers

PMID21310769
PMCPMC3750985

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.