ArticleClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2011
Functional imaging of sleep vertex sharp transients.
Article in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Role of the Amygdala in the Complex Relationship Between Sleep and Anxiety.International journal of molecular sciences · 2026Review
- Sleep neuroimaging: Review and future directions.Journal of sleep research · 2025Review
- Qualitative and Quantitative Comparative Analysis of Common Normal Variants and Physiological Artifacts in MEG and EEG.Brain topography · 2025Article
- Article
- Article
- Tracking brain arousal fluctuations with fMRI.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Article
- Functional connectivity homogeneity correlates with duration of temporal lobe epilepsy.Epilepsy & behavior : E&B · 2015Article
- Are Absence Epilepsy and Nocturnal Frontal Lobe Epilepsy System Epilepsies of the Sleep/Wake System?Behavioural neurology · 2015Review
- Article
- Identifying the sources of the pulse artefact in EEG recordings made inside an MR scanner.NeuroImage · 2013Article
- Prospective active marker motion correction improves statistical power in BOLD fMRI.NeuroImage · 2013Article
- Effect of lateralized temporal lobe epilepsy on the default mode network.Epilepsy & behavior : E&B · 2012Article
- Functional MRI of sleep spindles and K-complexes.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveThe vertex sharp transient (VST) is an electroencephalographic (EEG) discharge that is an early marker of non-REM sleep. It has been recognized since the beginning of sleep physiology research, but its source and function remain mostly unexplained. We investigated VST generation using functional MRI (fMRI).
methodsSimultaneous EEG and fMRI were recorded from seven individuals in drowsiness and light sleep. VST occurrences on EEG were modeled with fMRI using an impulse function convolved with a hemodynamic response function to identify cerebral regions correlating to the VSTs. A resulting statistical image was thresholded at Z>2.3.
resultsTwo hundred VSTs were identified. Significantly increased signal was present bilaterally in medial central, lateral precentral, posterior superior temporal, and medial occipital cortex. No regions of decreased signal were present.
conclusionThe regions are consistent with electrophysiologic evidence from animal models and functional imaging of human sleep, but the results are specific to VSTs. The regions principally encompass the primary sensorimotor cortical regions for vision, hearing, and touch. SIGNIFICANCE: The results depict a network comprising the presumed VST generator and its associated regions. The associated regions functional similarity for primary sensation suggests a role for VSTs in sensory experience during sleep.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.