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ArticleCurrent infectious disease reports2011

Comprehensive Approaches to the Diagnosis and Treatment of HIV Infection in the Community: Can "Seek and Treat" Really Deliver?

Brian Conway, Harout Tossonian

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Article in Current infectious disease reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian ConwayDepartment of Anesthesiology, Pharmacology, and Therapeutics, Faculty of Medicine, University of British Columbia, 201-1200 Burrard Street, Vancouver, BC, V6Z2C7, Canada, bconway@exchange.ubc.ca.
Harout Tossonian

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For every two people starting on combination antiretroviral therapy (cART), five become infected with HIV. Current prevention strategies are inadequate, and it has been hypothesized that cART itself could be used as a tool for prevention, in combination with enhanced testing and access to treatment-the "seek and treat" approach. Ecologic and modeling data support this strategy, but many questions remain: how to optimize HIV testing, cART uptake and adherence, how to deal with treatment failure and toxicity, and how to implement integrated prevention strategies and deal with key comorbidities. Pilot studies (eg, HIV Prevention Trials Network 065) are underway to validate the approach under controlled circumstances before it is integrated into public health policy. As we redefine the potential benefits of cART on a broader scale, let us not sacrifice the gains that have been made until we are more certain of the potential benefits of the "seek and treat" strategy.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.