Evidence map›Paper›PMID 21308405›Full record

ArticleJournal of molecular histology2011

Immunolocalization and activity of the MMP-9 and MMP-2 in odontogenic region of the rat incisor tooth after post shortening procedure.

Jose Rosa Gomes, Nádia Fayez Omar, Juliana dos Santos Neves, Eliene Aparecida Orsini Narvaes, Pedro Duarte Novaes

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Article in Journal of molecular histology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Jose Rosa GomesDepartamento de Biologia Estrutural Molecular e Genética, UEPG, Avenue Carlos Cavalcanti, 4748, Ponta Grossa, PR, 84030-900, Brazil. osteoblasto@ig.com.br
Nádia Fayez Omar
Juliana dos Santos Neves
Eliene Aparecida Orsini Narvaes
Pedro Duarte Novaes
Methodist University of Piracicaba · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversidade Estadual de Ponta Grossa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MMP-9 and MMP-2 are metalloproteinases which degrade the denatured collagen fibers. However, there is no report about roles of these MMPs in the odontogenic region of the adult rat incisor tooth under different eruption conditions. Male Wistar rats were divided in a normofunctional group (NF) in which their lower teeth remained in a normal eruption. In a hypofunctional group (HP) rats underwent shortening of their lower left incisor tooth every 2 days during 12 days. The eruption rate as well as the expression and activities of MMP-9 and MMP-2 were evaluated using imunohistochemistry and zymography. Although the shortening increased the eruption rate, no changes in the MMP-9 and MMP-2 were observed. We conclude that in adult rats, in opposite to development of tooth, the MMP-9 and MMP-2 present in the odontogenic region does not seem to play a direct role in the remodeling matrix, even after post-shortening procedures which to lead an acceleration of the eruption process in the incisor.

Indexed as

OdontogenesisAmeloblastsAnimalsDental PapillaDental SacEnzyme AssaysIncisorMaleMatrix Metalloproteinase 2Matrix Metalloproteinase 9OdontoblastsRatsRats, WistarTooth EruptionMatrix Metalloproteinase 2Matrix Metalloproteinase 9Mmp2 protein, rat

Identifiers

PMID21308405
OpenAlexW2154659738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.