ArticlePlant molecular biology2011
Plant aquaporins with non-aqua functions: deciphering the signature sequences.
Article in Plant molecular biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 172 citations in OpenAlex.
- Cork oak aquaporins: functional diversity and regulation with insights into drought response.Plant cell reports · 2026Article
- Characterization of the aquaporin gene family in Pinus massoniana and functional analysis of PmNIP2;1 involved in high-temperature and drought stress.BMC plant biology · 2026Article
- Comparative analysis of the Aquaporin gene family in Cucurbitaceae: insights into evolutionary patterns and functional diversity.BMC plant biology · 2026Article
- Genome-Wide Identification and Expression Analysis of Aquaporin Gene Family in Tea Plant (Plants (Basel, Switzerland) · 2025Article
- Promoter of Vegetable PeaInternational journal of molecular sciences · 2024Article
- Article
- Genome-Wide Analysis of Aquaporins in Japanese Morning Glory (Plants (Basel, Switzerland) · 2023Article
- Genome-wide identification and biological relevance of broccoli aquaporins.The plant genome · 2022Article
- Overexpression of theInternational journal of molecular sciences · 2022Article
- Ubiquitin ligase OsRINGzf1 regulates drought resistance by controlling the turnover of OsPIP2;1.Plant biotechnology journal · 2022Article
- Genome-Wide Identification and Expression Analyses of the Aquaporin Gene Family in Passion Fruit (International journal of molecular sciences · 2022Article
- The plasma membrane-localized OsNIP1;2 mediates internal aluminum detoxification in rice.Frontiers in plant science · 2022Article
- The roles of selectivity filters in determining aluminum transport by AtNIP1;2.Plant signaling & behavior · 2021Article
- Functions of silicon in plant drought stress responses.Horticulture research · 2021Review
- Genome-Wide Identification, Structure Characterization, and Expression Pattern Profiling of the Aquaporin Gene Family inInternational journal of molecular sciences · 2021Article
- A bamboo leaf-specific aquaporin gene PePIP2;7 is involved in abiotic stress response.Plant cell reports · 2021Article
- Genetic variation of BnaA3.NIP5;1 expressing in the lateral root cap contributes to boron deficiency tolerance in Brassica napus.PLoS genetics · 2021Article
- Overexpression ofInternational journal of molecular sciences · 2021Article
- Molecular Characterization and Expression of Four Aquaporin Genes inPlants (Basel, Switzerland) · 2021Article
- Article
18 more citing papers are in PubMed but not listed here.
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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Research in recent years on plant Major Intrinsic Proteins (MIPs), commonly referred to as 'aquaporins', has seen a vast expansion in the substrates found to be transported via these membrane channels. The diversity in sizes, chemical nature and physiological significance of these substrates has meant a need to critically analyse the possible structural and biochemical properties of MIPs that transport these, in order to understand their roles. In this work we have undertaken a comprehensive analysis of all plant MIPs, coming from different families, that have been proven to transport ammonia, boron, carbon dioxide, hydrogen peroxide, silicon and urea. The sequences were analysed for all primary selectivity-related motifs (NPA motifs, ar/R filter, P1-P5 residues). In addition, the putative regulatory phosphorylation and glycosylation sites and mechanistic regulators such as loop lengths have been analysed. Further, nine specificity-determining positions (SDPs) were predicted for each group. The results show the ar/R filter residues, P2-P4 positions and some of the SDPs are characteristic for certain groups, and O-glycosylation sites are unique to a subgroup while N-glycosylation was characteristic of the other MIPs. Certain residues, especially in loop C, and structural parameters such as loop lengths also contribute to the uniqueness of groups. The comprehensive analysis makes significant inroads into appraising the intriguing diversity of plant MIPs and their roles in fundamental life processes, and provides tools for plant selections, protein engineering and transgenics.
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