ArticleEuropean journal of pediatrics2011
Diagnosis and management of acute pharyngitis in a paediatric population: a cost-effectiveness analysis.
Article in European journal of pediatrics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Economic Analyses of Respiratory Tract Infection Diagnostics: A Systematic Review.PharmacoEconomics · 2021Pooled it
- Rapid antigen detection and molecular tests for group A streptococcal infections for acute sore throat: systematic reviews and economic evaluation.Health technology assessment (Winchester, England) · 2020Pooled it
- Modalities of group A streptococcal prevention and treatment and their economic justification.NPJ vaccines · 2023Article
- Antimicrobial Stewardship Strategies Including Point-of-Care Testing (POCT) for Pediatric Patients with Upper-Respiratory-Tract Infections in Primary Care: A Systematic Review of Economic Evaluations.Antibiotics (Basel, Switzerland) · 2022Review
- Using point-of-care diagnostic testing for improved antibiotic prescription: an economic model.Health economics review · 2021Article
- A Review ofPathogens (Basel, Switzerland) · 2021Review
- [Twenty-five myths in infectious diseases in primary care associated with overdiagnosis and overtreatment].Atencion primaria · 2018Review
- Efficiency of a clinical prediction model for selective rapid testing in children with pharyngitis: A prospective, multicenter study.PloS one · 2017Article
- Abdominal pain and nausea in the diagnosis of streptococcal pharyngitis in boys.International journal of general medicine · 2017Article
- [Recommendations for management of acute pharyngitis in adults].Enfermedades infecciosas y microbiologia clinica · 2016Review
- Effects of meteorologic factors and schooling on the seasonality of group A streptococcal pharyngitis.International journal of biometeorology · 2016Article
- Review
- [Recommendations for management of acute pharyngitis in adults].Atencion primaria · 2015Article
- [Diagnosis of streptococcal pharyngotonsillitis in children and adolescents: clinical picture limitations].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2014Article
- Streptococcal pharyngitis in children: to treat or not to treat?European journal of pediatrics · 2014Review
- No evidence for the effectiveness of systemic corticosteroids in acute pharyngitis, community-acquired pneumonia and acute otitis media.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013Review
- [Consensus document on the diagnosis and treatment of acute tonsillopharyngitis].Anales de pediatria (Barcelona, Spain : 2003) · 2011Article
- Recommendations for management of acute pharyngitis in adults.Acta otorrinolaringologica espanolaReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acute pharyngitis is one of the most frequent causes of primary care physician visits; however, there is no agreement about which is the best strategy to diagnose and manage acute pharyngitis in children. The aim of the current study was to evaluate the cost-effectiveness of the recommended strategies to diagnose and manage acute pharyngitis in a paediatric population. A decision tree analysis was performed to compare the following six strategies: "treat all", "clinical scoring", "rapid test", "culture", "rapid test + culture" and "clinical scoring + rapid test". The cost data came from the Spanish National Health Service sources. Cost-effectiveness was calculated from the payer's perspective. Effectiveness was measured as the proportion of patients cured without complications from the disease and did not have any reaction to penicillin therapy; a sensitivity analysis was performed. The findings revealed that the "clinical scoring + rapid test" strategy is the most cost-effective, with a cost-effectiveness ratio of 50.72 <euro>. This strategy dominated all others except "culture", which was the most effective but also the most costly. The sensitivity analysis showed that "rapid test" became the most cost-effective strategy when the clinical scoring sensitivity was <91% and its specificity was ≤9%. In conclusion, the use of a clinical scoring system to triage the diagnoses and performing a rapid antigen test for those with a high score is the most cost-effective strategy for the diagnosis and management of acute pharyngitis in children. When the clinical scoring system has a low diagnostic accuracy, testing all patients with rapid test becomes the most cost-effective strategy.
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Registered trials
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