Evidence map›Paper›PMID 21307885›Full record

ArticleJournal of human hypertension2012

Polyunsaturated fatty acid intake and blood pressure in adolescents.

T A O'Sullivan, A P Bremner, L J Beilin, G L Ambrosini, T A Mori, R C Huang, W H Oddy

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Journal of human hypertension, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

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  11. Serum long-chain omega-3 polyunsaturated fatty acids and risk of orthostatic hypotension.Hypertension research : official journal of the Japanese Society of Hypertension · 2016
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

T A O'SullivanTelethon Institute for Child Health Research, Centre for Child Health Research, University of Western Australia, West Perth, Western Australia, Australia. t.osullivan@ecu.edu.au
A P Bremner
L J Beilin
G L Ambrosini
T A Mori
R C Huang
W H Oddy
University of Western Australia · AUThe Kids Research Institute Australia · AU

Funding

Medical Research Council MC_U105960389
6 · The paper itself

Abstract

Evidence that intake of polyunsaturated fatty acids (PUFAs) may modify blood pressure (BP) is generally limited to middle-aged or hypertensive populations. This study examined cross-sectional associations between BP and dietary intake of PUFAs in 814 adolescents aged 13-15 years participating in the Western Australian Pregnancy Cohort (Raine) Study. Fatty acid intakes were assessed using 3-day diet records and resting BP was determined using multiple oscillometric readings. In multivariate regression models, systolic BP was inversely associated with intakes of polyunsaturated (b=-0.436, P<0.01), omega-3 (b=-2.47, P=0.02), omega-6 (b=-0.362, P=0.04) and long chain omega-3 fatty acids (b=-4.37, P=0.04) in boys. Diastolic BP and mean arterial pressure were inversely associated with intakes of long chain omega-3 fatty acids in boys (b=-3.93, P=0.01, b=-4.05, P=0.01, respectively). For specific long-chain omega-3s, significant inverse associations were observed between eicosapentaenoic acid (EPA) and docosahexaenoic acid, such as systolic BP decreasing by 4.7 mm Hg (95% CI -9.3 to -0.1) for a quarter gram increase in EPA, but no significant associations were observed with docosapentaenoic acid. No significant associations were observed in girls, or with the omega-6 to omega-3 ratio. Our results suggest that gender may moderate relationships between fatty acid intake and BP in adolescence.

Indexed as

Blood PressureAdolescentCross-Sectional StudiesDietary Fats, UnsaturatedDiet RecordsFatty Acids, Omega-3Fatty Acids, Omega-6Fatty Acids, UnsaturatedFemaleFollow-Up StudiesHumansMaleSex FactorsWestern AustraliaDietary Fats, UnsaturatedFatty Acids, Omega-3Fatty Acids, Omega-6Fatty Acids, Unsaturated

Identifiers

PMID21307885
OpenAlexW1975243262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.