ArticleJournal of neurophysiology2011
Temporal coding of taste in the parabrachial nucleus of the pons of the rat.
Article in Journal of neurophysiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 29 citations in OpenAlex.
- Whole-brain efferent and afferent connectivity of mouse ventral tegmental area melanocortin-3 receptor neurons.The Journal of comparative neurology · 2021Article
- Neural Coding of Food Is a Multisensory, Sensorimotor Function.Nutrients · 2021Review
- Satb2 neurons in the parabrachial nucleus mediate taste perception.Nature communications · 2021Article
- Glucagon-Like Peptide-1 (GLP-1) in the Integration of Neural and Endocrine Responses to Stress.Nutrients · 2020Review
- Cortical processing of chemosensory and hedonic features of taste in active licking mice.Journal of neurophysiology · 2020Article
- The Paraventricular Hypothalamus Regulates Satiety and Prevents Obesity via Two Genetically Distinct Circuits.Neuron · 2019Article
- Recognizing Taste: Coding Patterns Along the Neural Axis in Mammals.Chemical senses · 2019Review
- Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus.Frontiers in neural circuits · 2018Article
- Article
- Feed-Forward Propagation of Temporal and Rate Information between Cortical Populations during Coherent Activation in Engineered In Vitro Networks.Frontiers in neural circuits · 2016Article
- State Dependency of Chemosensory Coding in the Gustatory Thalamus (VPMpc) of Alert Rats.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Spatiotemporal Coding of Individual Chemicals by the Gustatory System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Bursting by taste-responsive cells in the rodent brain stem.Journal of neurophysiology · 2015Article
- Parabrachial calcitonin gene-related peptide neurons mediate conditioned taste aversion.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Taste coding in the parabrachial nucleus of the pons in awake, freely licking rats and comparison with the nucleus of the solitary tract.Journal of neurophysiology · 2014Article
- The role of vagal neurocircuits in the regulation of nausea and vomiting.European journal of pharmacology · 2014Review
- Article
- Subdiaphragmatic vagotomy reduces intake of sweet-tasting solutions in rats.Neural regeneration research · 2013Article
- Temporal characteristics of gustatory responses in rat parabrachial neurons vary by stimulus and chemosensitive neuron type.PloS one · 2013Article
- Inactivation of basolateral amygdala specifically eliminates palatability-related information in cortical sensory responses.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Recent studies have provided evidence that temporal coding contributes significantly to encoding taste stimuli at the first central relay for taste, the nucleus of the solitary tract (NTS). However, it is not known whether this coding mechanism is also used at the next synapse in the central taste pathway, the parabrachial nucleus of the pons (PbN). In the present study, electrophysiological responses to taste stimuli (sucrose, NaCl, HCl, and quinine) were recorded from 44 cells in the PbN of anesthetized rats. In 29 cells, the contribution of the temporal characteristics of the response to the discrimination of various taste qualities was assessed. A family of metrics that quantifies the similarity of two spike trains in terms of spike count and spike timing was used. Results showed that spike timing in 14 PbN cells (48%) conveyed a significant amount of information about taste quality, beyond what could be conveyed by spike count alone. In another 14 cells (48%), the rate envelope (time course) of the response contributed significantly more information than spike count alone. Across cells there was a significant correlation (r = 0.51; P < 0.01) between breadth of tuning and the proportion of information conveyed by temporal dynamics. Comparison with previous data from the NTS (Di Lorenzo PM and Victor JD. J Neurophysiol 90: 1418-31, 2003 and J Neurophysiol 97: 1857-1861, 2007) showed that temporal coding in the NTS occurred in a similar proportion of cells and contributed a similar fraction of the total information at the same average level of temporal precision, even though trial-to-trial variability was higher in the PbN than in the NTS. These data suggest that information about taste quality conveyed by the temporal characteristics of evoked responses is transmitted with high fidelity from the NTS to the PbN.
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