ArticleThe Plant cell2011
Crosstalk between Hsp90 and Hsp70 chaperones and heat stress transcription factors in tomato.
Article in The Plant cell, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 176 papers, 2 of them syntheses that pooled it.
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Who cites it
176 citing papers in PubMed, 2 syntheses or guidelines pooled it, 383 citations in OpenAlex.
- Pooled it
- Transcriptomic Landscape of Herbivore Oviposition in Arabidopsis: A Systematic Review.Frontiers in plant science · 2021Pooled it
- Heat stress responses of plants during adaptation to high temperature environments: A review of recent advances and insights.Plant signaling & behavior · 2026Review
- A novel CsRNF-CsHSF24-CsF3'5'H2 module regulates epigallocatechin gallate biosynthesis in Camellia sinensis.The Plant journal : for cell and molecular biology · 2026Article
- Principles and mechanisms of plant acclimation to heat stress.Nature reviews. Molecular cell biology · 2026Review
- Climate Warming and Plant Disease: Mechanistic Insights Into Pathogenic Stress Resilience.Plant, cell & environment · 2026Review
- Adaptive response to long-term high temperatures during the reproductive development in Arabidopsis thaliana.Planta · 2026Article
- Temperature regulation in plants: From molecular mechanisms to climate-resilient crop improvement.Journal of integrative plant biology · 2026Review
- Myo-inositol mitigates heat-induced leaf senescence by enhancing antioxidant defense, sugar metabolism, and heat shock pathway in creeping bentgrass.BMC plant biology · 2026Article
- Selection of heat stress-tolerant cultivars from radish and analysis of gene expression under high-temperature.Genes & genomics · 2026Article
- Genome-Wide Identification, Expression Analysis ofPlants (Basel, Switzerland) · 2026Article
- TaHST2 silencing shapes basal heat tolerance in allohexaploid wheat.Nature plants · 2026Article
- Circular RNA Vv-circCOR27 modulates thermotolerance through attenuating VvHSP90.2b-VvHsfA7a interaction in grapevine.The New phytologist · 2026Article
- Genome-wide identification of Hsf gene family in citrus and functional analysis of CsHsfA1a in heat stress response.Plant cell reports · 2026Article
- Molecular mechanisms and breeding strategies for heat tolerance in vegetable crops under global warming.Horticulture research · 2026Article
- Genome-wide identification, characterization and expression analysis of the HSP70 gene family in seagrass Zostera marina under abiotic stress.BMC plant biology · 2026Article
- Genome-Wide Identification and Systematic Analysis of theInternational journal of molecular sciences · 2026Article
- Genome-wide comparative analysis of the HSP90 gene family in four Ipomoea species and functional insights into the potentiality of IbHSP90-2 in low temperature tolerance.Frontiers in plant science · 2026Article
- Protein Post-Translational Modifications in Plant Abiotic Stress Responses.Plants (Basel, Switzerland) · 2025Review
- Review
116 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress transcription factors (Hsfs) regulate gene expression in response to environmental stress. The Hsf network in plants is controlled at the transcriptional level by cooperation of distinct Hsf members and by interaction with chaperones. We found two general mechanisms of Hsf regulation by chaperones while analyzing the three major Hsfs, A1, A2, and B1, in tomato (Solanum lycopersicum). First, Hsp70 and Hsp90 regulate Hsf function by direct interactions. Hsp70 represses the activity of HsfA1, including its DNA binding, and the coactivator function of HsfB1 in the complex with HsfA2, while the DNA binding activity of HsfB1 is stimulated by Hsp90. Second, Hsp90 affects the abundance of HsfA2 and HsfB1 by modulating hsfA2 transcript degradation involved in regulation of the timing of HsfA2 synthesis. By contrast, HsfB1 binding to Hsp90 and to DNA are prerequisites for targeting this Hsf for proteasomal degradation, which also depends on a sequence element in its carboxyl-terminal domain. Thus, HsfB1 represents an Hsp90 client protein that, by interacting with the chaperone, is targeted for, rather than protected from, degradation. Based on these findings, we propose a versatile regulatory regime involving Hsp90, Hsp70, and the three Hsfs in the control of heat stress response.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.