ArticleDevelopment (Cambridge, England)2011
A landmark-free morphometric staging system for the mouse limb bud.
Article in Development (Cambridge, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- CSF1R+ Macrophages and Osteoclasts Are Essential for Limb Bone Development During Embryogenesis.Journal of developmental biology · 2026Article
- Evolutionary transfer learning enables organism-wide inference of mammalian enhancer landscapes.bioRxiv : the preprint server for biology · 2026Article
- A comprehensive embryonic staging series of the turtle Trachemys scripta.Developmental dynamics : an official publication of the American Association of Anatomists · 2026Article
- Limblab: pipeline for 3D analysis and visualisation of limb bud gene expression.BMC bioinformatics · 2026Article
- Of Mice and Men: Temporal Comparison of Femoral Shaft Fracture Healing After Intramedullary Nailing: Retrospective Observational Study of Modified Radiographic Union Scores for Tibia.The Journal of bone and joint surgery. American volume · 2025Observational
- Large deformation diffeomorphic mapping of 3D shape variation reveals two distinct mandible and head capsule morphs inEcology and evolution · 2024Article
- Article
- Translating the Timing of Developmental Benchmarks in Short-Tailed Opossums (Monodelphisdomestica) to Facilitate Comparisons with Commonly Used Rodent Models.Brain, behavior and evolution · 2024Article
- Accurate staging of chick embryonic tissues via deep learning of salient features.Development (Cambridge, England) · 2023Article
- A single-cell transcriptional timelapse of mouse embryonic development, from gastrula to pup.bioRxiv : the preprint server for biology · 2023Article
- TATTOO-seq delineates spatial and cell type-specific regulatory programs in the developing limb.Science advances · 2022Article
- Setd5 is required in cardiopharyngeal mesoderm for heart development and its haploinsufficiency is associated with outflow tract defects in mouse.Genesis (New York, N.Y. : 2000) · 2021Article
- LAMA: automated image analysis for the developmental phenotyping of mouse embryos.Development (Cambridge, England) · 2021Article
- It takes two: Building the vertebrate skull from chondrocranium and dermatocranium.Vertebrate zoology · 2020Article
- It's about Time: Ossification Center Formation in C57BL/6 Mice from E12⁻E16.Journal of developmental biology · 2018Article
- A quantitative method for staging mouse embryos based on limb morphometry.Development (Cambridge, England) · 2018Article
- A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5).Journal of anatomy · 2017Article
- Representation of anatomy in online atlases and databases: a survey and collection of patterns for interface design.BMC developmental biology · 2016Article
- Geometric Morphometrics on Gene Expression Patterns Within Phenotypes: A Case Example on Limb Development.Systematic biology · 2016Article
- 4D atlas of the mouse embryo for precise morphological staging.Development (Cambridge, England) · 2015Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
We have created a 2D morphometric analysis of the developing mouse hindlimb bud. This analysis has provided two useful resources for the study of limb development. First, a temporally accurate numerical description of shape changes during normal mouse limb development. Second, a web-based morphometric staging system, which has the advantage of being easy to use, and with a reproducibility of about ±2 hours. It allows users to upload a dorsal-view photo of a limb bud, draw a spline curve and thereby stage the bud within a couple of minutes. We describe how the system is constructed, its robustness to user variation and illustrate one application: the accurate tracking of spatiotemporal dynamics of gene expression patterns.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.