Evidence map›Paper›PMID 21306972›Full record

ArticleEnvironmental health perspectives2011

The International Collaboration on Air Pollution and Pregnancy Outcomes: initial results.

Jennifer D Parker, David Q Rich, Svetlana V Glinianaia, Jong Han Leem, Daniel Wartenberg, Michelle L Bell, Matteo Bonzini, Michael Brauer, Lyndsey Darrow, Ulrike Gehring and 17 more

Abstract read
In one paragraph

Article in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
  2. Review
  3. Climate change, women's health, and the role of obstetricians and gynecologists in leadership.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2021
    Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Ambient Air Pollution and Adverse Pregnancy Outcomes in Wuhan, China.Research report (Health Effects Institute) · 2016
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

Jennifer D ParkerNational Center for Health Statistics, Centers for Disease Control and Prevention, Hyattsville, Maryland 20782, USA. jdparker@cdc.gov
David Q Rich
Svetlana V Glinianaia
Jong Han Leem
Daniel Wartenberg
Michelle L Bell
Matteo Bonzini
Michael Brauer
Lyndsey Darrow
Ulrike Gehring
Nelson Gouveia
Paolo Grillo
Eunhee Ha
Edith H van den Hooven
Bin Jalaludin
Bill M Jesdale
Johanna Lepeule
Rachel Morello-Frosch
Geoffrey G Morgan
Rémy Slama
Frank H Pierik
Angela Cecilia Pesatori
Sheela Sathyanarayana
Juhee Seo
Matthew Strickland
Lillian Tamburic
Tracey J Woodruff

Funding

Effect of Air Pollution and Traffic on Birth OutcomesR01ES016317 · NIEHS · YALE UNIVERSITY · PI BELANGER, KATHLEEN, BELL, MICHELLE L · 2008 to 2012
$2.9M
NIEHS NIH HHS 1R01ES016317NIEHS NIH HHS R01 ES016317
6 · The paper itself

Abstract

backgroundThe findings of prior studies of air pollution effects on adverse birth outcomes are difficult to synthesize because of differences in study design.

objectivesThe International Collaboration on Air Pollution and Pregnancy Outcomes was formed to understand how differences in research methods contribute to variations in findings. We initiated a feasibility study to a) assess the ability of geographically diverse research groups to analyze their data sets using a common protocol and b) perform location-specific analyses of air pollution effects on birth weight using a standardized statistical approach.

methodsFourteen research groups from nine countries participated. We developed a protocol to estimate odds ratios (ORs) for the association between particulate matter ≤ 10 μm in aerodynamic diameter (PM₁₀) and low birth weight (LBW) among term births, adjusted first for socioeconomic status (SES) and second for additional location-specific variables.

resultsAmong locations with data for the PM₁₀ analysis, ORs estimating the relative risk of term LBW associated with a 10-μg/m³ increase in average PM₁₀ concentration during pregnancy, adjusted for SES, ranged from 0.63 [95% confidence interval (CI), 0.30-1.35] for the Netherlands to 1.15 (95% CI, 0.61-2.18) for Vancouver, with six research groups reporting statistically significant adverse associations. We found evidence of statistically significant heterogeneity in estimated effects among locations.

conclusionsVariability in PM₁₀-LBW relationships among study locations remained despite use of a common statistical approach. A more detailed meta-analysis and use of more complex protocols for future analysis may uncover reasons for heterogeneity across locations. However, our findings confirm the potential for a diverse group of researchers to analyze their data in a standardized way to improve understanding of air pollution effects on birth outcomes.

Indexed as

Pregnancy OutcomeAir PollutionBirth WeightCohort StudiesFeasibility StudiesFemaleHumansInfant, Low Birth WeightInfant, NewbornInternational CooperationParticle SizeParticulate MatterPilot ProjectsPregnancyPremature BirthResearch DesignParticulate Matter

Identifiers

PMID21306972
PMCPMC3222970

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.