ReviewCurrent opinion in biotechnology2011
Bioconjugation of hydrogels for tissue engineering.
Review in Current opinion in biotechnology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Hydrogel Conjugation: Engineering of Hydrogels for Drug Delivery.Pharmaceutics · 2025Review
- Building Fucoidan/Agarose-Based Hydrogels as a Platform for the Development of Therapeutic Approaches against Diabetes.Molecules (Basel, Switzerland) · 2023Article
- NVCL-Based Hydrogels and Composites for Biomedical Applications: Progress in the Last Ten Years.International journal of molecular sciences · 2022Review
- Thermo-responsive imprinted hydrogel with switchable sialic acid recognition for selective cancer cell isolation from blood.Bioactive materials · 2021Article
- Nature-Derived and Synthetic Additives to poly(ɛ-Caprolactone) Nanofibrous Systems for Biomedicine; an Updated Overview.Frontiers in chemistry · 2021Review
- From Dermal Patch to Implants-Applications of Biocomposites in Living Tissues.Molecules (Basel, Switzerland) · 2020Review
- A Reversible and Repeatable Thiol-Ene Bioconjugation for Dynamic Patterning of Signaling Proteins in Hydrogels.ACS central science · 2018Article
- Biocomposite nanofiber matrices to support ECM remodeling by human dermal progenitors and enhanced wound closure.Scientific reports · 2017Article
- Molecular modeling to predict peptide accessibility for peptide-functionalized hydrogels.Biointerphases · 2017Article
- Biomolecular engineering for nanobio/bionanotechnology.Nano convergence · 2017Review
- Bioresponsive Hydrogels: Chemical Strategies and Perspectives in Tissue Engineering.Gels (Basel, Switzerland) · 2016Review
- Xylan hemicellulose improves chitosan hydrogel for bone tissue regeneration.Polymers for advanced technologies · 2016Article
- Designing Visible Light-Cured Thiol-Acrylate Hydrogels for Studying the HIPPO Pathway Activation in Hepatocellular Carcinoma Cells.Macromolecular bioscience · 2016Article
- Rheological and Mechanical Behavior of Silk Fibroin Reinforced Waterborne Polyurethane.Polymers · 2016Article
- Synthetic mimics of the extracellular matrix: how simple is complex enough?Annals of biomedical engineering · 2015Review
- Micropatterned cell-cell interactions enable functional encapsulation of primary hepatocytes in hydrogel microtissues.Tissue engineering. Part A · 2014Article
- Vascular smooth muscle cell optimization of vasculogenesis within naturally derived, biodegradable, hybrid hydrogel scaffolds.Plastic and reconstructive surgery · 2013Article
- Engineering synthetic hydrogel microenvironments to instruct stem cells.Current opinion in biotechnology · 2013Review
- The influence of matrix degradation and functionality on cell survival and morphogenesis in PEG-based hydrogels.Macromolecular bioscience · 2013Article
- Stiffness and adhesivity control aortic valve interstitial cell behavior within hyaluronic acid based hydrogels.Acta biomaterialia · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
Success of tissue engineered constructs in regenerative medicine is limited by the lack of cellmatrix interactions to guide devleopment of the seeded cells into the desired tissue. This review highlights the most exciting developments in bioconjugation of synthetic hydrogels targeted to tissue engineering. Application of conjugation techniques has resulted in the synthesis of novel biomimetic cell-responsive hydrogels to control the cascade of cell migration, adhesion, survival, differentiation, and maturation to the desired lineage concurrent with matrix remodeling. The future outlook includes developing conjugated patterned hydrogel matrices, developing novel hydrogel matrices to support self-renewal and pluripotency of embryonic and adult stem cells, and merging 3D printing with bioconjugation to fabricate hydrogels with anatomical arrangement of cells and biomolecules.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.