ArticleInfluenza and other respiratory viruses2011
Influenza and other respiratory viruses in three Central American countries.
Article in Influenza and other respiratory viruses, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 4 syntheses or guidelines pooled it, 44 citations in OpenAlex.
- Hospital utilization rates for influenza and RSV: a novel approach and critical assessment.Population health metrics · 2021Pooled it
- The burden of respiratory syncytial virus in adults: a systematic review and meta-analysis.Epidemiology and infection · 2020Pooled it
- Single and multiple respiratory virus infections and severity of respiratory disease: a systematic review.Paediatric respiratory reviews · 2014Pooled it
- Burden of influenza in Latin America and the Caribbean: a systematic review and meta-analysis.Influenza and other respiratory viruses · 2013Pooled it
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- Epidemiology of respiratory viruses in patients with severe acute respiratory infections and influenza-like illness in Suriname.Influenza and other respiratory viruses · 2021Article
- Viral and bacterial coinfection among hospitalized children with respiratory tract infections.American journal of infection control · 2020Article
- Human Parvovirus 4: A harmless bystander or a pathogen of severe acute respiratory illness.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Viral Etiology of Acute Respiratory Infections in Pediatric Patients in Lebanon.Mediterranean journal of hematology and infectious diseases · 2019Article
- Prevalence of respiratory viruses among children hospitalized from respiratory infections in Shenzhen, China.Virology journal · 2016Article
- Viral Etiology of acute respiratory tract infections in hospitalized children and adults in Shandong Province, China.Virology journal · 2015Article
- Risk factors for febrile respiratory illness and mono-viral infections in a semi-closed military environment: a case-control study.BMC infectious diseases · 2015Article
- The clinical and etiological characteristics of influenza-like illness (ILI) in outpatients in Shanghai, China, 2011 to 2013.PloS one · 2015Article
- Influenza-like illness sentinel surveillance in one hospital in Medellin, Colombia. 2007-2012.Influenza and other respiratory viruses · 2015Article
- Comparison of a new transport medium with universal transport medium at a tropical field site.Diagnostic microbiology and infectious disease · 2014Article
- Non-rhinovirus enteroviruses associated with respiratory infections in Peru (2005-2010).Virology journal · 2014Article
- A 3-year prospective study of the epidemiology of acute respiratory viral infections in hospitalized children in Shenzhen, China.Influenza and other respiratory viruses · 2014Article
- Comparative epidemiology of human metapneumovirus- and respiratory syncytial virus-associated hospitalizations in Guatemala.Influenza and other respiratory viruses · 2014Article
- Is influenza-like illness a useful concept and an appropriate test of influenza vaccine effectiveness?Vaccine · 2014Review
- Respiratory viral pathogens among Singapore military servicemen 2009-2012: epidemiology and clinical characteristics.BMC infectious diseases · 2014Article
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Authors and funding
17 authors at 7 institutions in 8 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite the disease burden imposed by respiratory diseases on children in Central America, there is a paucity of data describing the etiologic agents of the disease.
aimsTo analyze viral etiologic agents associated with influenza-like illness (ILI) in participants reporting to one outpatient health center, one pediatric hospital, and three general hospitals in El Salvador, Honduras, and Nicaragua Material &
methodsBetween August 2006 and April 2009, pharyngeal swabs were collected from outpatients and inpatients. Patient specimens were inoculated onto cultured cell monolayers, and viral antigens were detected by indirect and direct immunofluorescence staining.
resultsA total of 1,756 patients were enrolled, of whom 1,195 (68.3%) were under the age of 5; and 183 (10.4%) required hospitalization. One or more viral agents were identified in 434 (24.7%) cases, of which 17 (3.9%) were dual infections. The most common viruses isolated were influenza A virus (130; 7.4% of cases), respiratory syncytial virus (122; 6.9%), adenoviruses (63; 3.6%), parainfluenza viruses (57; 3.2%), influenza B virus (47; 2.7% of cases), and herpes simplex virus 1 (22; 1.3%). In addition, human metapneumovirus and enteroviruses (coxsackie and echovirus) were isolated from patient specimens. DISCUSSION: When compared to the rest of the population, viruses were isolated from a significantly higher percentage of patients age 5 or younger. The prevalence of influenza A virus or influenza B virus infections was similar between the younger and older age groups. RSV was the most commonly detected pathogen in infants age 5 and younger and was significantly associated with pneumonia (p < 0.0001) and hospitalization (p < 0.0001).
conclusionGenetic analysis of influenza isolates identified A (H3N2), A (H1N1), and B viruses. It also showed that the mutation H274Y conferring resistance to oseltamivir was first detected in Honduran influenza A/H1N1 strains at the beginning of 2008. These data demonstrate that a diverse range of respiratory pathogens are associated with ILI in Honduras, El Salvador, and Nicaragua. RSV infection in particular appears to be associated with severe disease in infants in the region.
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