Evidence map›Paper›PMID 21304548›Full record

ReviewNature reviews. Neuroscience2011

Molecular mechanisms of mechanotransduction in mammalian sensory neurons.

Patrick Delmas, Jizhe Hao, Lise Rodat-Despoix

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 199 papers.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

199 citing papers in PubMed.

  1. Trial
  2. Article
  3. An Innervated Human Skin Equivalent that Electrically Encodes Mechanical and Thermal Stimuli.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  4. Review
  5. Peripheral mechanisms of tactile sensation in fish.Current opinion in neurobiology · 2026
    Review
  6. Novel Role for CGRP in Aqueous Humor Outflow.Investigative ophthalmology & visual science · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Molecular divergence ofZoological research · 2026
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Patrick DelmasCentre de Recherche en Neurobiologie et Neurophysiologie de Marseille, UMR 6231, Centre National de la Recherche Scientifique, Université de la Méditerranée, CS80011, Boulevard Pierre Dramard, 13344 Marseille Cedex 15, France. patrick.delmas@univmed.fr
Jizhe Hao
Lise Rodat-Despoix

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The somatosensory system mediates fundamental physiological functions, including the senses of touch, pain and proprioception. This variety of functions is matched by a diverse array of mechanosensory neurons that respond to force in a specific fashion. Mechanotransduction begins at the sensory nerve endings, which rapidly transform mechanical forces into electrical signals. Progress has been made in establishing the functional properties of mechanoreceptors, but it has been remarkably difficult to characterize mechanotranducer channels at the molecular level. However, in the past few years, new functional assays have provided insights into the basic properties and molecular identity of mechanotransducer channels in mammalian sensory neurons. The recent identification of novel families of proteins as mechanosensing molecules will undoubtedly accelerate our understanding of mechanotransduction mechanisms in mammalian somatosensation.

Indexed as

AnimalsEvoked Potentials, SomatosensoryHumansMechanoreceptorsMechanotransduction, CellularSensory Receptor CellsTouch

Identifiers

PMID21304548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.