ArticleNeurorehabilitation and neural repair2011
Doublet electrical stimulation enhances torque production in people with spinal cord injury.
Article in Neurorehabilitation and neural repair, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Strategies for Rapid Muscle Fatigue Reduction during FES Exercise in Individuals with Spinal Cord Injury: A Systematic Review.PloS one · 2016Pooled it
- Effects of ankle continuous passive motion on soleus hypertonia in individuals with cerebral palsy: A case series.Biomedical journal · 2022Article
- Heterogeneity of the strength response to progressive resistance exercise training in older adults: Contributions of muscle contractility.Experimental gerontology · 2021Article
- Reactive stepping with functional neuromuscular stimulation in response to forward-directed perturbations.Journal of neuroengineering and rehabilitation · 2017Article
- Effects of Constant and Doublet Frequency Electrical Stimulation Patterns on Force Production of Knee Extensor Muscles.PloS one · 2016Article
- Investigation of different stimulation patterns with doublet pulses to reduce muscle fatigue.Journal of rehabilitation and assistive technologies engineeringArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundMuscle fatigue prevents repetitive use of paralyzed muscle after spinal cord injury (SCI).
objectiveThis study compared the effects of hybrid patterns of muscle stimulation in individuals with acute and chronic SCI.
methodsIndividuals with chronic (n = 11) or acute paralysis (n = 3) underwent soleus muscle activation with a constant (CT) or doublet (DT) stimulation train before and at various times after a fatigue protocol.
resultsThe chronically paralyzed soleus was highly fatigable with a fatigue index (FI) of 19% ± 6%, whereas the acutely paralyzed soleus was fatigue resistant (FI = 89% ± 8%). For the chronically paralyzed group, the DT protocol caused less than 5% improvement in peak and mean force relative to the CT protocol before fatigue; however, after fatigue the DT protocol caused an increase in peak and mean force (>10%), compared with the CT protocol (P < .05). As the chronically paralyzed muscle developed low-frequency fatigue, the DT protocol became more effective than the CT protocol (P < .05). The DT protocol increased the rate of torque development before fatigue (42% ± 78%), after fatigue (62% ± 52%), and during recovery (87% ± 54% to 101% ± 56%; P < .05). The acutely paralyzed group showed minimal change in peak and mean torque with the DT protocol.
conclusionsChronic reduced activity is associated with muscle adaptations (slow to fast) that render the muscle more amenable to force enhancement through doublet train activation after fatigue. These findings are applicable to patients using neuromuscular stimulation.
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Registered trials
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