ReviewBiochimica et biophysica acta2011
Protein folding at single-molecule resolution.
Review in Biochimica et biophysica acta, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed.
- Viruses under mechanical force: Implications and applications.Virus research · 2026Review
- The Effect of β-Sheet Secondary Structure on All-β Proteins by Molecular Dynamics Simulations.Molecules (Basel, Switzerland) · 2024Article
- Effects of Residual Composition and Distribution on the Structural Characteristics of the Protein.International journal of molecular sciences · 2022Article
- Depicting Conformational Ensembles of α-Synuclein by Single Molecule Force Spectroscopy and Native Mass Spectroscopy.International journal of molecular sciences · 2019Article
- Direct Single-Molecule Observation of Sequential DNA Bending Transitions by the Sox2 HMG Box.International journal of molecular sciences · 2018Article
- Review
- A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution.Nature communications · 2016Article
- Single-molecule folding mechanisms of the apo- and Mg(2+)-bound states of human neuronal calcium sensor-1.Biophysical journal · 2015Article
- Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date?Archives of biochemistry and biophysics · 2014Review
- Application of fluorescence resonance energy transfer in protein studies.Journal of molecular structure · 2014Article
- Single-Molecule Analysis of CytochromeThe journal of physical chemistry letters · 2013Article
- Regulated unfolding of proteins in signaling.FEBS letters · 2013Review
- Counteracting chemical chaperone effects on the single-molecule α-synuclein structural landscape.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Single-molecule observation of helix staggering, sliding, and coiled coil misfolding.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Disentangling subpopulations in single-molecule FRET and ALEX experiments with photon distribution analysis.Biophysical journal · 2012Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The protein folding reaction carries great significance for cellular function and hence continues to be the research focus of a large interdisciplinary protein science community. Single-molecule methods are providing new and powerful tools for dissecting the mechanisms of this complex process by virtue of their ability to provide views of protein structure and dynamics without associated ensemble averaging. This review briefly introduces common FRET and force methods, and then explores several areas of protein folding where single-molecule experiments have yielded insights. These include exciting new information about folding landscapes, dynamics, intermediates, unfolded ensembles, intrinsically disordered proteins, assisted folding and biomechanical unfolding. Emerging and future work is expected to include advances in single-molecule techniques aimed at such investigations, and increasing work on more complex systems from both the physics and biology standpoints, including folding and dynamics of systems of interacting proteins and of proteins in cells and organisms. This article is part of a Special Issue entitled: Protein Dynamics: Experimental and Computational Approaches.
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Registered trials
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