Evidence map›Paper›PMID 21303640›Full record

ReviewJournal of diabetes science and technology2011

Noninvasive diagnostic devices for diabetes through measuring tear glucose.

Jin Zhang, William Hodge, Cindy Hutnick, Xianbin Wang

Open access · bronzeAbstract readEvaluation StudyReview
In one paragraph

Review in Journal of diabetes science and technology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 147 citations in OpenAlex.

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  15. Observational
  16. Advances in Biosensors for Continuous Glucose Monitoring Towards Wearables.Frontiers in bioengineering and biotechnology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jin ZhangDepartment of Chemical and Biochemical Engineering, University of Western Ontario, London, Ontario, Canada. jzhang@eng.uwo.ca
William Hodge
Cindy Hutnick
Xianbin Wang
Western University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This article reviews the development of a noninvasive diagnostic for diabetes by detecting ocular glucose. Early diagnosis and daily management are very important to diabetes patients to ensure a healthy life. Commercial blood glucose sensors have been used since the 1970s. Millions of diabetes patients have to prick their finger for a drop of blood 4-5 times a day to check blood glucose levels--almost 1800 times annually. There is a strong need to have a noninvasive device to help patients to manage the disease easily and painlessly. Instead of detecting the glucose in blood, monitoring the glucose level in other body fluids may provide a feasible approach for noninvasive diagnosis and diabetes control. Tear glucose has been studied for several decades. This article reviews studies on ocular glucose and its monitoring methods. Attempts to continuously monitor the concentration of tear glucose by using contact lens-based sensors are discussed as well as our current development of a nanostructured lens-based sensor for diabetes. This disposable biosensor for the detection of tear glucose may provide an alternative method to help patients manage the disease conveniently.

Indexed as

Biosensing TechniquesBlood GlucoseBlood Glucose Self-MonitoringContact LensesDiabetes MellitusGlucoseHumansModels, BiologicalModels, MolecularTearsBlood GlucoseGlucose

Identifiers

PMID21303640
PMCPMC3045221
OpenAlexW2138192406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.