Evidence map›Paper›PMID 21302180›Full record

Trial reportSubstance abuse2011

Testing an optimized community-based human immunodeficiency virus (HIV) risk reduction and antiretroviral adherence intervention for HIV-infected injection drug users.

Michael M Copenhaver, I-Ching Lee, Arthur Margolin, Robert D Bruce, Frederick L Altice

Abstract readClinical Trial
In one paragraph

Trial report in Substance abuse, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Public health implications for adequate transitional care for HIV-infected prisoners: five essential components.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2011
    Article
  16. Article
  17. Article
  18. Harm reduction: compassionate care of persons with addictions.Medsurg nursing : official journal of the Academy of Medical-Surgical Nurses
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael M CopenhaverDepartment of Allied Health Sciences, University of Connecticut, Storrs, Connecticut 06269-2101, USA. michael.copenhaver@uconn.edu
I-Ching Lee
Arthur Margolin
Robert D Bruce
Frederick L Altice

Funding

Enhancing Health Outcomes Among HIV+ Substance AbusersK24DA017072 · NIDA · YALE UNIVERSITY · PI ALTICE, FREDERICK LEWIS · 2003 to 2012
$1.5M
Substance Abuse, HIV and HCV Treatments to Improve Health Outcomes in Drug UsersK23DA022143 · NIDA · YALE UNIVERSITY · PI BRUCE, ROBERT D · 2006 to 2010
$881k
Optimizing HIV Risk Reduction for HIV Positive IDUsK23DA017015 · NIDA · UNIVERSITY OF CONNECTICUT STORRS · PI COPENHAVER, MICHAEL · 2003 to 2006
$619k
NIDA NIH HHS K23 DA017015NIDA NIH HHS K23 DA022143NIDA NIH HHS K24 DA017072PHS HHS K24 017072
6 · The paper itself

Abstract

The authors conducted a preliminary study of the 4-session Holistic Health for HIV (3H+), which was adapted from a 12-session evidence-based risk reduction and antiretroviral adherence intervention. Improvements were found in the behavioral skills required to properly adhere to HIV medication regimens. Enhancements were found in all measured aspects of sex-risk reduction outcomes, including HIV knowledge, motivation to reduce sex-risk behavior, behavioral skills related to engaging in reduced sexual risk, and reduced risk behavior. Improvements in drug use outcomes included enhancements in risk reduction skills as well as reduced heroin and cocaine use. Intervention effects also showed durability from post-intervention to the follow-up assessment point. Females responded particularly well in terms of improvements in risk reduction skills and risk behavior. This study suggests that an evidence-based behavioral intervention may be successfully adapted for use in community-based clinical settings where HIV-infected drug users can be more efficiently reached.

Indexed as

Drug MonitoringRisk Reduction BehaviorAdultAnti-HIV AgentsBehavior TherapyConnecticutDrug UsersFemaleHealth Knowledge, Attitudes, PracticeHIV InfectionsHolistic HealthHumansMaleMiddle AgedMotivationRisk-TakingAnti-HIV Agents

Identifiers

PMID21302180
PMCPMC3071583

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.