Evidence map›Paper›PMID 21299297›Full record

Trial reportHealth psychology : official journal of the Division of Health Psychology, American Psychological Association2011

Exercise improves executive function and achievement and alters brain activation in overweight children: a randomized, controlled trial.

Catherine L Davis, Phillip D Tomporowski, Jennifer E McDowell, Benjamin P Austin, Patricia H Miller, Nathan E Yanasak, Jerry D Allison, Jack A Naglieri

3 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Health psychology : official journal of the Division of Health Psychology, American Psychological Association, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 327 papers, 27 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
327citing papers in PubMed, 27 pooled it
61.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02788851 naunknown statusnot on this mapstarted 2016, after this paper: background citation

The Relative Efficacy of Aerobic Exercise in the Treatment of Adults With Attention Deficit Hyperactivity Disorder (ADHD) Versus Medication Only and the Combination of the Two: A Pilot Study

TypeinterventionalSponsorMcGill University Health Centre/Research Institute of the McGill University Health CentreRan2016 to 2018Enrolled70ConditionsAttention Deficit Hyperactivity Disorder (ADHD)ArmsMethylphenidate compounds and /or Amphetamine compounds and/or Strattera or Guanfacine, Aerobic Exercise
NCT04282460 nacompletednot on this mapstarted 2020, after this paper: background citation

A Randomized Clinical Trial of Ba Duan Jin in Treatment of Attention Deficit Hyperactivity Disorder With Hyperactive-Impulsive Symptom

TypeinterventionalSponsorChildren's Hospital of Fudan UniversityRan2020 to 2023Enrolled120ConditionsAttention Deficit Hyperactivity DisorderArmsBaduanjin practice, Regular physical exercise
NCT06496503 nacompletednot on this mapstarted 2024, after this paper: background citation

Effect of a School Intervention With Physical Activity on Executive Functions and Relationships With Cardiorespiratory Fitness and Motor Coordination: Randomized Clinical Trial

TypeinterventionalSponsorState University of LondrinaRan2024 to 2025Enrolled100ConditionsHealthy LifestyleArmsPhysical activity Protocol
3 · Its place in the literature

Who cites it

327 citing papers in PubMed, 27 syntheses or guidelines pooled it, 898 citations in OpenAlex.

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267 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Catherine L DavisGeorgia Prevention Institute, Pediatrics, Medical College of Georgia, Augusta, GA 30912, USA. cadavis@mcg.edu
Phillip D Tomporowski
Jennifer E McDowell
Benjamin P Austin
Patricia H Miller
Nathan E Yanasak
Jerry D Allison
Jack A Naglieri
University of Georgia · USAugusta University · USGeorge Mason University · US

Funding

Exercise Dose and Insulin Sensitivity in Obese ChildrenR01DK060692 · NIDDK · MEDICAL COLLEGE OF GEORGIA (MCG) · PI DAVIS, CATHERINE LUCY · 2003 to 2006
$2.2M
Exercise &Overweight Children's Cognition &AchievementR01DK070922 · NIDDK · MEDICAL COLLEGE OF GEORGIA (MCG) · PI DAVIS, CATHERINE LUCY · 2005 to 2006
$459k
NIDDK NIH HHS DK60692NIDDK NIH HHS DK70922NIDDK NIH HHS R01 DK060692NIDDK NIH HHS R01 DK070922
6 · The paper itself

Abstract

objectiveThis experiment tested the hypothesis that exercise would improve executive function.

designSedentary, overweight 7- to 11-year-old children (N = 171, 56% girls, 61% Black, M ± SD age = 9.3 ± 1.0 years, body mass index [BMI] = 26 ± 4.6 kg/m², BMI z-score = 2.1 ± 0.4) were randomized to 13 ± 1.6 weeks of an exercise program (20 or 40 min/day), or a control condition.

main outcome measuresBlinded, standardized psychological evaluations (Cognitive Assessment System and Woodcock-Johnson Tests of Achievement III) assessed cognition and academic achievement. Functional MRI measured brain activity during executive function tasks.

resultsIntent to treat analysis revealed dose-response benefits of exercise on executive function and mathematics achievement. Preliminary evidence of increased bilateral prefrontal cortex activity and reduced bilateral posterior parietal cortex activity attributable to exercise was also observed.

conclusionConsistent with results obtained in older adults, a specific improvement on executive function and brain activation changes attributable to exercise were observed. The cognitive and achievement results add evidence of dose-response and extend experimental evidence into childhood. This study provides information on an educational outcome. Besides its importance for maintaining weight and reducing health risks during a childhood obesity epidemic, physical activity may prove to be a simple, important method of enhancing aspects of children's mental functioning that are central to cognitive development. This information may persuade educators to implement vigorous physical activity.

Indexed as

CognitionOverweightBrainChildExecutive FunctionExerciseFemaleHumansMagnetic Resonance ImagingMale

Identifiers

PMID21299297
PMCPMC3057917
OpenAlexW2118921112

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.